A Case Report on Scleroderma: A Diagnostic Dilema
Ch. K. V. L. S. N. Anjana Male, Hari Chandana Varikallu, Tirumalasetty Sai Swapna, N. Dileep, S. Hemanth Durga Prasad, Sarath Nalla
Journal of Pharmaceutical Research International · pp. 251–255 · Published 6 Aug 2021
10.9734/jpri/2021/v33i40A32241Abstract
Scleroderma is a rare heterogenous group of autoimmune fibrosing disorder that mainly exists in two forms; localized scleroderma (LS) and systemic sclerosis (SSc). It involves thickening of the skin at fingers region extending from proximal to metacarpophalangeal joints. The diagnostic criteria of scleroderma include past history of patient, symptoms of patient, serology, and skin biopsy. The morbidity and mortality are much worse for SSc with the patients are at risk for life threatening lung, heart and other visceral organ fibrosis and vasculopathy. There is no drug that can cure or stop scleroderma over fibrosis, but certain drugs regulate the symptoms associated with it and boost the patient's quality of life, particularly steroidal creams that help alleviate swelling, joint pain, loosen tight skin; blood pressure drugs that dilate blood vessels; immunosuppressive agents. If the disease is severe amputation is necessary.
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