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Research Article Open access CC BY 4.0

A Comparative Phytochemistry and Antioxidant Activity of Sida acuta L. and Sida cordifolia Linn.

Seema Kanwar, Radhika Khandelwal, Shilpi Rijhwani, Reenu Agarwal

Asian Journal of Biology · pp. 130–141 · Published 17 Jul 2025

10.9734/ajob/2025/v21i7535

Abstract

Sida acuta L. and Sida cordifolia Linn. (Malavaceae) have a long history of being used for their medicinal properties. These plants have been considered for use in Ayuveda, Traditional Chinese medicine, Indigenous healing practices in the form of crude extract, homemade tea, dry powder and many more. The Present study was carried out to compare phytochemical constituents and antioxidant activity of Sida acuta L and Sida cordifolia Linn. For qualitative analysis, methanol and ethyl acetate extracts were tested for various phytoconstituents, while for quantitative analysis and antioxidant activity, methanolic extracts of leaf and stem were subjected for various tests. The results of qualitative analysis showed that the methanolic extracts of both plants were able to extract more phytoconstituents compare to ethyl acetate. For quantitative analysis, leaf extract of Sida cordifolia Linn. was found to have the highest amount of total phenolic content (0.0852±0.006 mgGAE/g), total flavonoids content (0.1194±0.097mgQE/g), and lipid (1.66±0.016mg/g) while Sida acuta L. leaf extract possessed highest amount of alkaloids (1.257± 0.086mg/g). The antioxidant activity was found highest in Sida cordifolia Linn. leaf (70.59%±0.0017) at 1mg/ml. Above study shows that Sida cordifolia Linn. is rich in secondary metabolites and possesses the highest antioxidant activity.

Phytochemical methanol ethyl acetate total phenolic content total flavonoid content antioxidant activity

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