A Comparative Study of the Anti-Candidal Activity of Four Medicinal Plants Used in Côte d'Ivoire
Yapo Y. C. V., Kra A. K. M., Konan G. K. N. A., Kple T. K. M., Money Y. U., Kouame C. C., Bolou G. E. K., N’guessan J. D., Djaman A. J.
International Journal of Biochemistry Research & Review · pp. 48–55 · Published 15 Nov 2023
10.9734/ijbcrr/2023/v32i8834Abstract
Some plants groups are used by traditional practitioners to treat infectious diseases. The ongoing development of antibiotic resistance continues to have a lasting impact on public health. This study aimed to assess the potential activity of the medicinal plants found in Ivorian soil. Spectrometric measurements was employed in addition to the moss test, revealed the presence of sterols and polyterpenes, polyphenolic compounds, saponins, quinones, alkaloids, and tannins in the extracts of the four plants studied. The use of the double dilution method in tilted tubes revealed the Anti-candida potential of the plant extracts. Results revealed showed that the hydroethanolic extract of T. mantaly produced the lowest MFC (3.125 mg/mL) and IC50 (0.3 mg/mL) values. It was followed by Z. gilletii (MFC = 3.125 mg/mL; IC50 = 0.62 mg/mL) and T. catappa (MFC = 3.125 mg/mL; IC50 = 0.68 mg/mL). No significant inhibition was observed with the extracts of A. occidentale. This study contributes to the valorization of medicinal plants and the floral heritage of Côte d'Ivoire.
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