Skip to content
Research Article Open access CC BY 4.0

A Rarely Seen Side Effect of Sulfasalazine: Yellowish Colour in Toenails

Ibrahim Tekeoğlu, Sinem Sağ, Ayhan Kamanli, Mustafa Serdar Sağ, Teoman Erdem

International Journal of Medical and Pharmaceutical Case Reports · pp. 1–4 · Published 5 Oct 2015

10.9734/IJMPCR/2015/21498

Abstract

Sulfasalazine (SLZ) was the slow acting medication most often used to treat patients with ankylosing spondylitis whose symptoms were not adequately controlled with nonsteroidal anti-inflammatory drugs, exercise, and rehabilitative therapies. Sulfasalazine is an older generation anti-rheumatic drug first synthesized in the 1940s as a combination of an antibiotic (sulfa pyridine) and an nonsteroidal anti‑inflammatory drug (5-aminosalicylic acid). Most patients can take sulfasalazine with few side effects. In this study we present a rarely seen side effect of SLZ on a patient with ankylosing spondylitis whose toenails turned gradually yellow in two years duration.

Ankylosing spondylitis sulfasalazine yellowish toenails.

Cited by 2

Sulfasalazine-Induced Nail Changes: A Unique Clinical Observation

Shrinivas Patil, Anuj Bhatnagar, Debdeep Mitra · Dermatology Practical & Conceptual · 2024

Showing 1 of 2 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

28

Page views

0

PDF downloads

3

Outbound clicks

2

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.