Skip to content
Research Article Open access CC BY 4.0

A Review of CD4 Positive T Lymphocytes Counts among HIV Positive Patients Attending a Nigerian Teaching Hospital

S. I. Nwadioha, M. S. Odimayo, G. T. A. Jombo, E. O. Nwokedi Prince, M. Atef

Microbiology Research Journal International · pp. 1–7 · Published 23 Jul 2015

10.9734/BMRJ/2015/19294

Abstract

Aims and Objectives:  To determine the baseline CD4 positive T lymphocytes count of HIV/AIDS treatment naïve adults clients presenting for the first time treatment in Benue State University Teaching Hospital. Subjects and Methods: A total of 700 subjects age between 18 years to 70 years, were recruited for the study, comprising 600 HIV sero-positive patients and 100 healthy controls in Benue State University Teaching Hospital, Makurdi from 2013 to 2014. The CD4 counts of the subjects were evaluated using a Partec flow cytometer. Results: CD4 count of 200-299 cells/μl peaked with 25% (n=150/600) [control; 0% (n= 0/100)]. The study also showed that 44% (266/600) of HIV subjects had acquired immunodeficiency syndrome as defined by low CD4 counts below 200 cells/μl. Seventy-five per cent (n=451/600) of our patients would require to be placed on antiretroviral therapy with CD4 count below 350 cells/μl. At CD4 350 baseline criterion, age group 20-29 years had the highest demand 35% (160/451) for ARV followed by age groups 30-39 and 40-49 years  with 28% (128/451) and  22% (98/451) respectively. Conclusion: There is a high prevalence of acquired immunodeficiency syndrome among the young active productive age group as defined by CD4 counts below 200 cells/μl. The strict adopting of the ART WHO 2010 scale- up criteria doubles the number of the HIV clients that would qualify for ART with its attendant health benefits on the long run.

CD4 counts HIV patients Nigeria

References (13)

  1. 1 Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies [DOI]
  2. 2 An overview of the relative risks of different sexual behaviours on HIV transmission [DOI]
  3. 3 The Story of CD4+CD28−T Cells Revisited: Solved or Still Ongoing? [DOI]
  4. 4 Establishment of Reference Values of CD4 and CD8 Lymphocyte Subsets in Healthy Nigerian Adults [DOI]
  5. 5 CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria [DOI]
  6. 6 The Treatment of Patients With HIV [DOI]
  7. 7 Baseline CD4 lymphocyte count among HIV patients in Kano, Northern Nigeria [DOI]
  8. 8 Changes in CD4+ and CD8+ cell levels during pregnancy and post partum in women seropositive and seronegative for human immunodeficiency virus-1 [DOI]
  9. 9 CD4 Count and anti Retroviral Therapy for HIV Positive Patients with Cancer in Nigeria -A Pilot Study [DOI]
  10. 10 Haematological aspects of antiretroviral naïve HIV patients in a Nigerian tertiary hospital: laboratory and clinical considerations. [DOI]
  11. 11 CD4 Cell Count of HIV-Positive Patients in Awka, South East Nigeria [DOI]
  12. 12 Normal CD4 T-lymphocyte baseline in healthy HIV-negative pregnant women [DOI]
  13. 13 CD4 Cell Count in HIV positive subjects in Asaba, South South Nigeria – [DOI]

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

29

Page views

0

PDF downloads

5

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.