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Research Article Open access CC BY 4.0

Anti-restenotic Therapies for Peripheral Arterial Disease

Vincent Varghese, Jon C. George

Journal of Advances in Medicine and Medical Research · pp. 1–9 · Published 27 Jun 2015

10.9734/BJMMR/2015/18492

Abstract

Defining the ideal treatment for peripheral arterial disease remains an ongoing endeavor. The initial treatment standard of balloon angioplasty and stenting has produced suboptimal long-term outcomes due to in-stent restenosis and the subsequent need for revascularization. Yet, the field of endovascular medicine has seen an explosion of new technologies, which have yielded promising early and mid-term results. Anti-restenotic drug therapies have the potential to reduce neointimal hyperplasia, in-stent restenosis, and improve vessel patency in femoro-popliteal arteries. We discuss herein current and future drug eluting technologies across various delivery methods and platforms.

Peripheral arterial disease stent restenosis anti-restenotic therapy drug-coated balloon drug-eluting stent.

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