Antibacterial Activity of Zea mays Silks and Husks Crude Extract on Biofilm Producing Multi-Drug Resistant Bacteria from Urinary Catheters
Olanrewaju Samson Odelola, Victor Olusegun Oyetayo, Ayodele Oluwayemisi Ogundare, Funmilola Oluyemi Omoya, Olugbenga Emmanuel Ajayi
International Journal of Pathogen Research · pp. 37–51 · Published 19 May 2023
10.9734/ijpr/2023/v12i2224Abstract
Aims: This study was carried out to investigate the in-vitro antibacterial effect of the crude extracts of Corn (Zea mays) silks and husks on selected biofilm producing multi-drug resistant bacteria isolated from urinary catheter tips. Study Design: Experimental design. Place and Duration of Study: This study was conducted at the Federal University of Technology, Akure (FUTA) Ondo State, Nigeria. Methodology: Bacterial isolates from urinary catheter tips were screened for biofilm production. The biofilm producing isolates were subjected to commercial antibiotics and isolates resistant to more than three classes of antibiotics were used for the study. Methanol and distilled water were used as extracting solvents for the corn silks and husks. The antibacterial activity and phytochemical analysis of the extracts were carried out using standard procedures. Results: The phytochemical analysis of the methanol and aqueous extracts of corn husks and silks revealed the presence of saponins, tannins, flavonoids, steroids, terpenoids and cardiac glycosides. The aqueous extract of corn husk showed highest inhibitory effects on Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Escherichia coli and Coagulase-Negative Staphylococci with zones of inhibition ranging from 14.80 ± 1.89 mm to 24.40 ± 2.51 mm at 200 mg/mL. Proteus mirabilis exhibited resistance against all the extracts. Conclusion: Findings from this study revealed the antibacterial potential of corn silks and husks extracts at varying concentrations. The potency of aqueous extract of husk at lower concentration (200 mg/mL) suggests its potential use in the treatment of urinary tract bacteria especially Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Coagulase-Negative Staphylococci.
References (15)
- 1 Antibiotic resistance and its cost: is it possible to reverse resistance? [DOI]
- 2 Historical review of medicinal plants′ usage [DOI]
- 3 Bacterial adhesion and biofilms on surfaces [DOI]
- 4 Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix [DOI]
- 5 Inhibition of Bacterial Biofilm Formation and Swarming Motility by a Small Synthetic Cationic Peptide [DOI]
- 6 Corn Silk (Stigma Maydis) in Healthcare: A Phytochemical and Pharmacological Review [DOI]
- 7 A Novel Signaling Network Essential for Regulating Pseudomonas aeruginosa Biofilm Development [DOI]
- 8 Patterns of antibiotic sensitivity of bacterial pathogens among urinary tract infections (UTI) patients in a Pakistani population [DOI]
- 9 Antimicrobial Activities of Extracts and Flavonoid Glycosides of Corn Silk (Zea mays L) [DOI]
- 10 Corn - Production and Human Health in Changing Climate [DOI]
- 11 Antimicrobial Susceptibility Pattern of Urinary Pathogens Isolated from Two Tertiary Hospitals in Southwestern Nigeria [DOI]
- 12 Bacterial type I Signal Peptidases as Antibiotic Targets [DOI]
- 13 The antimicrobial pattern and phytochemical properties of the leaf extracts of Senna podocarpa [DOI]
- 14 Evaluation of Antagonistic Action of Corn Silk Extract Towards Various Fungal and Bacterial Pathogens [DOI]
- 15 International Journal of Biotechnology for Wellness Industries [DOI]
Cited by 5
Olanrewaju Samson Odelola, Victor Olusegun Oyetayo, Ayodele Oluwayemisi Ogundare, Babatunde Ogunlade · Journal of Applied Life Sciences International · 2023
Tanya Marok, Prasad Rasane, Sawinder Kaur · Open Agriculture · 2024
Iram Liaqat, Ramsha Ibtisam, Muhammad Imran Hussain · Journal of Oleo Science · 2025
Showing 3 of 5 known citations — external sources report more than can currently be individually listed.
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