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Research Article Open access CC BY 4.0

Antibacterial Effect of Cinnamon Oil against Uropathogenic Multidrug Resistant

Rana Thamer Hadi Alkhafaji, M. Jayashankar

Journal of Pharmaceutical Research International · pp. 6–15 · Published 21 Apr 2022

10.9734/jpri/2022/v34i33A36121

Abstract

Cinnamon is known for its antimicrobial activity and the aim of this study was to investigate the effect of its essential oil against ten of the multidrug-resistant uropathogenic by agar well diffusion assays.  The diameters of the inhibition zone to the Cinnamon oil were 27 mm for S. aureus, 24 mm for E coli,    20 mm for P.aeruginosa,   22 mm for K.pneumoniae, 23 mm for E.aerogenes & P. mirabilis,    24 mm for E. faecalis, and   27 mm for N.gonorrhoeae, A.baumanni, S.epidermis. In this study, the antimicrobial effects of the cinnamon essential oil are evaluated by determining the minimum inhibitory concentration (MIC), the inhibition zone, and minimum bactericidal concentration (MBC). Cinnamon was the most effective agent in inhibiting A.baumanni, N.gonorrhoeae, S. epidermis, E. faecalis and E. coli with the lowest MIC (0.0313%) while S.aureus, E. aerogenes and P. aeruginosa with MIC (0.125%) while P. mirabilis was 0.0625% in our study. The MBC was 0. 25% for A.baumanni, 0.5 % for N, gonorrhoeae, S. epidermis, E. faecalis, and K. pneumonia, while 1% S.aureus, E. aerogenes, P. mirabilis, E. coli, and P. aeruginosa.

Antimicrobial cinnamon oil agar well diffusion MIC & MBC uropathogenic

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