Antibiotic Sensitivity Profile of Catheter-Associated Urinary Tract Infection at Hasan Sadikin Hospital, Bandung, Indonesia

Abstract

Background: Urinary tract infections are the most common type of healthcare-associated infection, accounting for more than 30% reported by acute care hospitals. Virtually all healthcare-associated UTIs are caused by instrumentation of the urinary tract. Catheter-associated urinary tract infection (CAUTI) has been associated with increased morbidity, mortality, hospital costs, and length of stay. In addition, bacteriuria commonly leads to unnecessary antimicrobial use. Understanding the patient profile is initial data that is important in case of CAUTI for future research. Aim: To find the antibiotic resistance pattern of bacterial infection of urinary Tract Infection associated with catheterization in Hasan Sadikin Hospital, Bandung. Methods: The Subject is a patient indicated for catheterization in Hasan Sadikin Hospital, Bandung, with the number of samples is 21 participants. The initial data are patient identity, blood, urine bacterial culture, and resistance examination results. Catheterization insertion is performed for 1 week, and the catheter tip is then prepared again for bacterial culture and resistance examination. CAUTI diagnosis is based on the recommendation of the CDC (Centers for Disease Control and Prevention). The data is processed and analyzed by a chi-square test, then presented in the table. Results: Twenty-one sample of 40 (52.5%) catheterized patients shows positive culture results. All Subjects are male, with an age range is between 18-73 years old. The 5th decade is the most often group of 9 patients (22.5%), 13 patients (61.9%) had urine culture findings showing E. coli bacteria in their results, 5 patients (23.8%) had urine culture findings showing Staphylococcus haemolyticus, one patient (4.8%) had findings showing Micrococcus, one patient (4.8%) had finding Acinetobacter baumanii and one patient (4.8%) had findings Pseudomonas aeruginosa. Netilmicin antibiotic is most sensitive, 6 of 12 patients (50%), and cefoperazone is found resistant in 10 of 10 patients (100%). Conclusion: Urinary tract infection associated catheterization is more common in the fifth decade of age and also in patients whose glucose level is above the normal value. The most common bacteria found is E coli, and the most sensitive antibiotic for the urinary tract is netilmicin, while the most resistant is cefoperazone