Antimicrobial and Wound Healing Activity of Gardenia aqualla Stem Bark Methanol Extract
Michael Anyekema, Lesley Sahber Kindzeka, Aristide Dzelamonyuy
Asian Journal of Biochemistry, Genetics and Molecular Biology · pp. 30–38 · Published 31 Aug 2021
10.9734/ajbgmb/2021/v9i130207Abstract
Aim: This study was aimed at examining the antimicrobial and wound healing activities of Gardenia aqualla stem bark methanol extract (GASBME) in order to provide scientific basis for its antimicrobial and wound healing properties. Methodology: Preliminary phytochemical screening was done and antimicrobial activity determined using some pathogenic micro-organisms were evaluated following its wound healing effectiveness in Wistar rats using the model of superficial skin excision wound. Data were analysed using one-way analysis of variance (ANOVA) followed by Dunnet’s t-test. Results: The results of preliminary phytochemical screening revealed the presence of carbohydrate, cardiac glycosides, saponins, flavonoids, triterpenes, tannins, alkaloids with anthraquinones being absent. The extract showed antimicrobial activity on Staphylococcus aureus, Corynebacterium ulcerans, Escherichia coli, Klebsiella pneumonia and Salmonella typhi and significant (p< 0.05, p< 0.001) decrease in wound measurement by the 11th day. Conclusion: This study demonstrated that GASBME possesses antimicrobial activity with wound healing properties that justifies the ethno-medicinal use of the plant in wound/ulcer healings.
Cited by 2
Azuka T H Mokogwu, E. Ekene, K. Amaihunwa · International Journal of Biomedical Science and Engineering · 2026
Showing 1 of 2 known citations — external sources report more than can currently be individually listed.
Related research
- Review: Parkia speciosa as Valuable, Miracle of Nature — shares topic coverage
- Urinary Pathogens amongst Parturients at the University of Port Harcourt Teaching Hospital, South-South, Nigeria — shares topic coverage
- Antimicrobial Studies on Leaf and Stem Extracts of Solanum erianthum — shares topic coverage
- An in-vitro Analysis of the Antioxidant and Antimicrobial Properties of the Methanol Extract of Hypoxis hemerocallideacorm (MEHHC) from Botswana — shares topic coverage
- Evaluation of Antimicrobial Potency and Phytochemical Screening of Persea americana Leaf Extracts against Selected Bacterial and Fungal Isolates of Clinical Importance — shares topic coverage
Article metrics
Real usage data collected on this platform.
8
Page views
0
PDF downloads
7
Outbound clicks
2
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.