Antimicrobial Resistance: Unexplained Failure to Antibiotic Therapy in a Case at Maluti Adventist Hospital Berea Lesotho
Lineo Nyenye, Azubuike Benjamin Nwako
Journal of Advances in Medical and Pharmaceutical Sciences · pp. 1–4 · Published 15 Jul 2022
10.9734/jamps/2022/v24i630305Abstract
Aim: The aim of the present study was to highlight the presence and problem of antimicrobial resistance in our setting. Case Presentation: We present a 17-year old female with yellow offensive vaginal discharge, itchiness and lower abdominal pain of about two-weeks duration. She was treated with antibiotics based on laboratory results of urine and high vaginal swabs. However, the symptoms persisted despite the treatment and high adherence to the medications. Discussion: Antimicrobial Resistance (AMR) presents a painful risk to human health and life around the globe. The efficacy and effectiveness of antimicrobial agents are now under massive threat from increasing resistance of disease pathogens to antimicrobial agents. The unexplained failure of antibiotic therapy occurred despite the prescription being based on sensitivity results from swab culture on two separate occasions. Conclusion: There is need for high index of suspicion of antimicrobial resistance by health workers. There is also need for rational prescription, dispensing and use of antimicrobial agents. Patients need increased access to high quality antimicrobial medicines and more awareness of the development, spread and prevention of antimicrobial resistance.
References (10)
- 1 Antibiotic resistance: a rundown of a global crisis [DOI]
- 2 Microbiological effects of sublethal levels of antibiotics [DOI]
- 3 Access to effective antimicrobials: a worldwide challenge [DOI]
- 4 Prevalence and Estimated Economic Burden of Substandard and Falsified Medicines in Low- and Middle-Income Countries [DOI]
- 5 Human, animal and environmental contributors to antibiotic resistance in low-resource settings: integrating behavioural, epidemiological and One Health approaches [DOI]
- 6 Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections: a prospective cohort study [DOI]
- 7 The Growing Threat of Antibiotic Resistance in Children [DOI]
- 8 Patient adherence to prescribed antimicrobial drug dosing regimens [DOI]
- 9 Medicines quality assurance to fight antimicrobial resistance [DOI]
- 10 Fighting poor-quality medicines in low- and middle-income countries: the importance of advocacy and pedagogy [DOI]
Cited by 2
Ergün Gültekin · Middle East Journal of Science · 2025
Showing 1 of 2 known citations — external sources report more than can currently be individually listed.
Related research
- Profile and Antimicrobial Resistance Patterns of Bacteria isolated from Patients with Respiratory Tract Infections in Ile-Ife Metropolis — shares topic coverage
- Carriage of Drug-Resistant Staphylococcus aureus in the Anterior Nares of a Healthy Student Population — shares topic coverage
- Prevalence, Aetiological Agents and Antimicrobial Resistance Patterns of Urinary Tract Infections among Pregnant Women Attending Mother and Child Hospital, Akure, South-West Nigeria — shares topic coverage
- Awareness of Antimicrobial Resistance among Primary Health Care Workers in Buyende District, Rural Eastern Uganda — shares topic coverage
- Acquisition of Antibiotic Resistance in Escherichia coli Exposed To a Locally Produced Herbal Drug — shares topic coverage
Article metrics
Real usage data collected on this platform.
26
Page views
0
PDF downloads
15
Outbound clicks
2
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.