Antiparasitic, Antibiofilm, and Mucolytic Activities of Mimosa pudica: An Integrative Literature Review

Abstract

Intestinal parasitic diseases remain a significant public health challenge, especially in tropical and subtropical regions. Mimosa pudica L., commonly known as “sensitive plant,” has been widely used in traditional medicine due to its antiparasitic, antibiofilm, and mucolytic properties. This study investigates, through in vitro and in vivo assays and a comprehensive literature review, the effectiveness of M. pudica extracts in eliminating parasites, disrupting pathogenic biofilms, and eliminating mucoid plaques. Additionally, it evaluates the phytochemical profile of the plant and its toxicity. The results confirm the multifunctional potential of Mimosa pudica, suggesting its application in intestinal detoxification protocols and chronic infection management. Furthermore, it discusses the mechanisms of action, the plant’s limitations, and outlines future clinical perspectives. The plant's ability to combat biofilms, reduce parasitic load, and assist in mucolytic processes makes it a promising candidate for integrative health approaches. While the current body of research provides valuable insights, further studies focusing on clinical trials to validate its therapeutic use in human populations and explore its full potential in therapeutic interventions are necessary. The investigation into the plant's efficacy, through rigorous clinical trials, can help validate its place in modern pharmacology and expand its application for gastrointestinal health.