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Research Article Open access CC BY 4.0

Automated Blood Analysers and Their Testing Principles: A Comparative Study

N. V. Hemanth Ragav, Palati Sinduja, R. Priyadharshini

Journal of Pharmaceutical Research International · pp. 294–301 · Published 29 Dec 2021

10.9734/jpri/2021/v33i63A35633

Abstract

Computerized hematology analyzers are the absolute most significant instruments in the present clinical laboratory.  Hematology analyzers are the principal supplies in clinical labs. A very good quality, high-volume analyzers convey dependable red platelet checks, platelet tallies, and 5-section differentials of white platelets, recognizing lymphocytes, monocytes, neutrophils, eosinophils, and basophils. CELL-DYN SapphireTM is a very good quality hematology analyzer made by Abbott Technologies. The UniCel® DxH 800 Analyzer is a quantitative, automated hematology analyzer developed for use in clinical laboratories for in vitro diagnostic screening of patient populations. XE-5000 is an automated hematology analyzer used in clinical laboratories for in vitro diagnostic. XE-5000 can examine and can give output for 67 parameters. The XN-2000 platform combines two investigative components that can be customized to suit a specific clinical application. Without the need for large track-based structures, costly stains, or reflexive testing, the ADVIA® 2120i Hematology Machine will fully simplify your hematology lab. Photometry is the method used in hemoglobin measurement. The traditional method for counting cells is electrical impulse, otherwise called as Coulter Principle. It is used in most hematology analyzers. In optical light scatter measurement, through a diluted blood spectrum a beam of laser light is passed and that is projected into the flow cell by hydrodynamic focusing. This review aimed to overview the working principle of various Hematological analyzers in common use.

Hematology analyzer photometry impedance light scatter flow cytometry innovative technique

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