Skip to content
Research Article Open access CC BY 3.0

Biological Importance of Phytochemicals from Calophyllum brasiliense Cambess

A. Bernabé-Antonio, L. P. Álvarez-Berber, F. Cruz-Sosa

Annual Research & Review in Biology · pp. 1502–1517 · Published 30 Jan 2014

10.9734/ARRB/2014/8597

Abstract

A great diversity of medicinal plants have been traditionally used against gastropathy, infections and inflammatory pathological ailments. C. brasiliense (Clusiaceae) is a large tree native to the tropical forest which thrives from Brazil to Mexico. It is a plant commonly used in traditional medicine against several diseases, infections and other pathological disorders. Phytochemical isolations of heartwood, leaves, stem bark, and seed oil have confirmed the existence of several coumarins, xanthones and triterpenes which have a wide biological activity against bacteria, protozoa, fungus, virus and cancer. C. brasiliense is highlighted as an important resource of calanolides, a dipyranocoumarins that inhibit reverse transcriptase of human immunodeficiency virus type 1 (HIV-1 RT). Despite having wide medicinal importance, the fact that in Mexico it is poorly known is causing a reduction of this species. In this regard, studies on preservation and production of chemical compounds by plant cell culture need to be developed. The aim of this review is to provide the general characteristics of C. brasiliense, the most common traditional uses, and its phytochemical constituents. In particular, we discussed extracts and phytochemical components that have displayed anticancer, antiviral, antimicrobial and antiparasitic activity reported in the current literature. In addition, we intended to inspire new studies on phytotherapy, bioproduction and conservation to be developed.

C. brasiliense Phytochemicals Bioactivity Calanolides VIH-1.

References (62)

  1. 1 Glossary of Indian Medicinal Plants
  2. 2 Production of plant secondary metabolites: a historical perspective [DOI]
  3. 3 Antiviral potentials of medicinal plants [DOI]
  4. 4 Medicinal Plants: A Source of Anti-Parasitic Secondary Metabolites [DOI]
  5. 5 Antibacterial activity of crude extracts from Mexican medicinal plants and purified coumarins and xanthones [DOI]
  6. 6 The Medicinal and Poisonous Plants of India
  7. 7 Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii [DOI]
  8. 8 Prevalence and Risk Factors for Helicobacter pylori Infection in Chinese Populations [DOI]
  9. 9 Antileishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis [DOI]
  10. 10 Cytotoxic effects of mammea type coumarins from Calophyllum brasiliense [DOI]
  11. 11 Novel Cytotoxic 4-Phenylfuranocoumarins from Calophyllum d ispar [DOI]
  12. 12 A revision of the Old World species of Calophyllum (Guttiferae) [DOI]
  13. 13 HIV-1 Inhibitory Compounds from Calophyllum brasiliense Leaves [DOI]
  14. 14 Inhibition of gastric H+,K+-ATPase activity by flavonoids, coumarins and xanthones isolated from Mexican medicinal plants [DOI]
  15. 15 Plants as a source of anti‐cancer and anti‐HIV agents [DOI]
  16. 16 The medicinal and poisonous plants of India [DOI]
  17. 17 Chemical Constituents of Calophyllum brasiliensis: Structure Elucidation of Seven New Xanthones and Their Cancer Chemopreventive Activity [DOI]
  18. 18 Natural products as leads to antitumor drugs [DOI]
  19. 19 Natural products in modern life science [DOI]
  20. 20 Antimicrobial Activity of Fractions and Compounds from Calophyllum brasiliense (Clusiaceae/Guttiferae) [DOI]
  21. 21 Gastroprotective effect from Calophyllum brasiliense Camb. bark on experimental gastric lesions in rats and mice [DOI]
  22. 22 Trypanocidal constituents in plants: 7. Mammea-type coumarins [DOI]
  23. 23 Inhibition of HIV-1 replication by a tricyclic coumarin GUT-70 in acutely and chronically infected cells [DOI]
  24. 24 Structure–activity relationship of natural and synthetic coumarins inhibiting the multidrug transporter P-glycoprotein [DOI]
  25. 25 Inhibition of leukemic cell growth by a novel anti‐cancer drug (GUT‐70) from calophyllum brasiliense that acts by induction of apoptosis [DOI]
  26. 26 Cytoprotective effect against UV-induced DNA damage and oxidative stress: Role of new biological UV filter [DOI]
  27. 27 In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb. [DOI]
  28. 28 Bioactive Pyranoxanthones from the Roots of Calophyllum blancoi [DOI]
  29. 29 Anti-HIV activity of natural triterpenoids and hemisynthetic derivatives 2004–2009 [DOI]
  30. 30 Effects of (−) mammea A/BB isolated from Calophyllum brasiliense leaves and derivatives on mitochondrial membrane of Leishmania amazonensis [DOI]
  31. 31 Inhibition of HIV-1 reverse transcriptase, toxicological and chemical profile of Calophyllum brasiliense extracts from Chiapas, Mexico [DOI]
  32. 32 Antiproliferative, cytotoxic and antitumour activity of coumarins isolated from Calophyllum brasiliense [DOI]
  33. 33 Comparing Conventional and Supercritical Extraction of (−)-Mammea A/BB and the Antioxidant Activity of Calophyllum brasiliense Extracts [DOI]
  34. 34 Efficacy of components from leaves of Calophyllum brasiliense against Leishmania (Leishmania) amazonensis [DOI]
  35. 35 Epimers from the leaves of Calophyllum inophyllum [DOI]
  36. 36 A New Biflavonoid from Calophyllum panciflorum with Antitumor-Promoting Activity [DOI]
  37. 37 HIV-1 Inhibition by Extracts of Clusiaceae Species from Mexico [DOI]
  38. 38 New and Antifungal Xanthones from Calophyllum caledonicum [DOI]
  39. 39 A polyisoprenylated ketone from Calophyllum enervosum [DOI]
  40. 40 Production of anti-HIV-1 calanolides in a callus culture of Calophyllum brasiliense (Cambes) [DOI]
  41. 41 Pharmacological and phytochemical investigations of different parts of Calophyllum brasiliense (Clusiaceae).
  42. 42 Apoptosis inducing activity of 4-substituted coumarins from Calophyllum brasiliense in human leukaemia HL-60 cells [DOI]
  43. 43 Activity of Extracts and Coumarins from the Leaves ofCalophyllum brasiliense. onLeishmania braziliensis. [DOI]
  44. 44 Calophyllum brasiliense Cambess.
  45. 45 Antifungal Xanthones from Calophyllum brasiliensis Heartwood [DOI]
  46. 46 First 2-Hydroxy-3-Methylbut-3-Enyl Substituted Xanthones Isolated From Plants: Structure Elucidation, Synthesis and Antifungal Activity [DOI]
  47. 47 Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Activity by Cordatolides Isolated fromCalophyllum cordato-oblongum [DOI]
  48. 48 Mucigerin, a new coumarin fromCalophyllum mucigerum(Guttiferae) [DOI]
  49. 49 Leaf Structure of Two Chemotypes of Calophyllum brasiliense from Mexico [DOI]
  50. 50 Amazonian Ethnobotanical Dictionary [DOI]
  51. 51 HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum [DOI]
  52. 52 PLANT CELL CULTURES AN ALTERNATIVE AND EFFICIENT SOURCE FOR THE PRODUCTION OF BIOLOGICALLY IMPORTANT SECONDARY METABOLITES [DOI]
  53. 53 Essential Oils Isolated from Myrtaceae Family as Natural Insecticides
  54. 54 Chromanones and Dihydrocoumarins from Calophyllum blancoi [DOI]
  55. 55 Pattern of anti-HIV dipyranocoumarin expression in callus cultures of Calophyllum inophyllum Linn. [DOI]
  56. 56 Antihyperglycemic Activity of Leaf Essential Oil of Citrus sinensis (L.) Osbeck on Alloxan- Induced Diabetic Rats [DOI]
  57. 57 A Revision of the Old World Species of Calophyllum (Guttiferae) [DOI]
  58. 58 Antibacterial and analgesic effects of the stem barks of Calophyllum inophyllum.
  59. 59 Natural products in modern life science [DOI]
  60. 60 Seroprevalence and risk factors for Helicobacter pylori infection [DOI]
  61. 61 Chromanones and Dihydrocoumarins from Calophyllum blancoi. [DOI]
  62. 62 Amazonian ethnobotanical dictionary [DOI]

Cited by 6

ESTABLISHMENT OF A CELL SUSPENSION CULTURE FROM Calophyllum brasiliense AND EVALUATION OF ITS ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY

D. Cisneros-Torres, F. Cruz-Sosa, M. P. Nicasio-Tórres · Revista Mexicana de Ingeniería Química · 2019

The Effectivity of Butanol Fraction of Calophyllum nodosum as Antiviral Drug to Dengue Virus Serotype 2 In Vitro

Syifa Salsabila, N. Calista, H. Desti · Proceedings of BROMO Conference · 2018

Showing 4 of 6 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

14

Page views

0

PDF downloads

0

Outbound clicks

6

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.