Skip to content
Research Article Open access CC BY 4.0

Blood Group Antigens Phenotype Frequencies among Pregnant Women in Sokoto State, Nigeria

H. A. Buhari, A. Sagir, S. A. Akuyam, O. Erhabor, A. A. Panti

International Blood Research & Reviews · pp. 134–140 · Published 23 Dec 2022

10.9734/ibrr/2022/v13i4293

Abstract

Background: Blood group antigens have been used to evaluate ethnic diversity of human populations and had been related to predisposing individuals to some diseases or may protect individuals against some diseases. They also play the most important role in success of pregnancy and blood transfusion. Aim: The aim is to determine the frequencies of some blood group antigens phenotype among pregnant women. Materials and Methods: The study is a cross sectional study   conducted in the department of obstetrics and gynaecology, antenatal clinic in Usmanu Danfodiyo Teaching Hospital Sokoto, from January 2020 to September 2020. This research included 1250 consecutively -recruited pregnant women on their first antenatal visit. The blood grouping were determined using standard tube techniques for ABO, MNSs, Duffy and Kidd antigens while column agglutination card was used for Rh C, E, c, e and Kell was utilized. Results: The sociodemographic characteristics revealed that the age range of the subject was 17-48 years .where majority were within the age between 21-30 years (61.3%). Majority of the pregnant women had their first antenatal visit during second trimester of their pregnancy (59.7%). The distribution of the ABO blood group revealed that 48.5% were group O, 27.3% were group B, 19.4% were group A and 4.8% were group AB. Out the subjects investigated, 93.1%, 30.2%, 24.6% and 90.2% were RhD, RhC, RhE, Rhc and Rhe positive respectively. The prevalence of M, S and s positive were 75.5%, 31.4% and 63.3% respectively. Among the subjects studied, 97.6% were Kell positive while 2.4% were kell negative. The prevalence of Duffy a and b antigen were 1.1% and 0.5% respectively and the prevalence of Kidd a and b phenotype positive were 15.9% and 21.7% respectively. Conclusion: The pattern of distribution of ABO, Rh, MSs, Duffy and Kidd blood groups antigens among pregnant women in Sokoto was in agreement with other populations while that of Kell blood group antigen is at variance with other population particularly among Caucasians. Data derived from this study will help policy makers make evidenced –based decisions on management of HDFN.

Blood group antigens phenotypes pregnant women Sokoto

References (18)

  1. 1 The blood group antigen factsbook [DOI]
  2. 2 Postgraduate Haematology [DOI]
  3. 3 Blood groups and human groups: Collecting and calibrating genetic data after World War Two [DOI]
  4. 4 International Society of Blood Transfusion Working Party on red cell immunogenetics and blood group terminology: Cancun report (2012) [DOI]
  5. 5 Do Sociodemographic Characteristics of Pregnant Women Determine their Perception of Antenatal Care Quality? [DOI]
  6. 6 Phenotype Frequencies of Major Blood Group Systems (Rh, Kell, Kidd, Duffy, MNS, P, Lewis, and Lutheran) Among Blood Donors in the Eastern Region of Saudi Arabia [DOI]
  7. 7 Prevalence of Red Blood Cell Major Blood Group Antigens and Phenotypes among Omani Blood Donors [DOI]
  8. 8 Blood Groups Distribution and Gene Diversity of the ABO and Rh (D)Lociin the Mexican Population [DOI]
  9. 9 Anaemia and thrombocytopenia among pregnant women attending Aminu Kano Teaching Hospital, Kano State, North Western Nigeria [DOI]
  10. 10 Rh antigen and phenotype frequencies and probable genotypes for the four main ethnic groups in Port Harcourt, Nigeria [DOI]
  11. 11 Red blood cell alloimmunization and minor red blood cell antigen phenotypes in transfused Ghanaian patients with sickle cell disease [DOI]
  12. 12 Frequencies of MNS Blood Group Antigens and Phenotypes in Southwestern Saudi Arabia [DOI]
  13. 13 The ABO and Rhesus groups in the north of Nigeria [DOI]
  14. 14 Rh antigens and phenotype frequencies of the Ibibio, Efik, and Ibo ethnic nationalities in Calabar, Nigeria [DOI]
  15. 15 Rh and Kell blood group antigen prevalence in a multi-ethnic cohort in Nigeria: implications for local transfusion service [DOI]
  16. 16 Distribution of ABO and rhesus blood groups in Abraka, Delta State, Nigeria.
  17. 17 A Survey of ABO, Rhesus (D) Antigen and Haemoglobin Genes Variants in Oyo State, Nigeria.
  18. 18 The Duffy blood group system in the Tunisian population [DOI]

Cited by 2

Investigation of haematological, inflammatory parameters and the incidence of alloimmunization in multi-transfused sickle cell diseased patients

Florence Ifechukwude Aboderin, Taofeeq Oduola, Glenda Mary Davison · Hematology, Transfusion and Cell Therapy · 2025

Showing 1 of 2 known citations — external sources report more than can currently be individually listed.

Related research

Article metrics

Real usage data collected on this platform.

45

Page views

0

PDF downloads

8

Outbound clicks

2

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.