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Research Article Open access CC BY 4.0

Case Report on Subacute Sclerosing Panencephalitis

Sweta Chavhan, Archana Maurya, Amruta Kothe

Journal of Pharmaceutical Research International · pp. 214–218 · Published 21 Dec 2021

10.9734/jpri/2021/v33i60B34607

Abstract

Introduction: Subacute sclerosing panencephalitis (SSPE), frequently referred as Dawson disease, is a kind of sclerosing  panencephalitis, and is an uncommon long-term, continuous cerebral inflammatory condition triggered by a gradual infection with particular faulty types of hyper mutated measles virus. Main Symptoms and/or Important Clinical Findings: Patient came with the complaint of gait abnormalities, sudden fall while walking, loss of speech, staring look, abnormal smile and loss of bladder control, hemiplegia and contracture of all four limbs, seizures, Grade III Malnutrition. The Main Diagnoses, Therapeutic Interventions, and Outcomes: Patient undergone investigation i.e. Blood Test: Hb- 9.8 gm%, TLC- 14,700/mm, Platelet- 2.24 lacs /cu.mm, Total Protein- 8.4 g/dl, HCT- 29.8, Serum Bilirubin- 1.0mg/dl, ALP- 99IU/L, Serum Urea-32mg/dl,SerumCreatinine-0.5mg/dl,SerumSodium-153meq/L,SerumPotassium-.2mmol/L. .CSF igg Measles test was done EEG which revealed burst of periodic complexes with well-preserved back ground activity. Doctor manages with Tab. Valparin 200mg BD, Tab. Frisium 5mg BD, Tab. Baclofen10mgBD,Tab. Samion D3 OD, Syp Q-Carni 5ml BD, Tab. Augment375mg BD. Outcome: After treatment, the child showed some improvement. The patient was admitted to Pediatric Ward No- 22, AVBRH with known case of Subacute sclerosing panencephalitis (SSPE) and he had complaint of swelling over right jaw with caries tooth since4month.

Subacute sclerosing panencephalitis Dawson disease hyper mutated measles virus cerebral inflammatory condition seizures infection

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