Colon Cancer with Complete Pathological Response to Only 1 Cycle of Capecitabine: Treatment Modification in the Perspective of COVID-19 Pandemic
Mussadique Ali Jhatial, Iqra Naeem, Naila Shaikh, Rizwan Masood Sheikh
International Journal of Medical and Pharmaceutical Case Reports · pp. 1–7 · Published 22 Nov 2021
10.9734/ijmpcr/2021/v14i430138Abstract
Incidence of colorectal cancer has surged in the past few decades, currently it accounts for approximately 10% cancer related mortality. Upfront curative surgery is the main stay of treatment for localized disease followed by adjuvant chemotherapy for high-risk disease; however, neo adjuvant chemoradiation followed by surgery and chemotherapy is a standard treatment for rectal cancer. Here, we present a case of a young male aged 33 years with eight months’ history of per rectal bleeding, associated with fever and weight loss who was later diagnosed as sigmoid colon adenocarcinoma. The patient managed to have only one cycle of neoadjuvant capecitabine, as his definitive surgery was delayed due to the rife in pandemic situation of Covid-19. Notably, follow up laparoscopic LAR specimen showed no residual disease, nevertheless, there was an eosinophilic abscess with a giant cell reaction and Ova of Ascaris lumbricoides, which seemingly contributed in achieving pathological complete response with minimal therapy.
References (11)
- 1 ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making [DOI]
- 2 CYTOKINE REGULATION OF HOST DEFENSE AGAINST PARASITIC GASTROINTESTINAL NEMATODES:Lessons from Studies with Rodent Models* [DOI]
- 3 Colorectal cancer [DOI]
- 4 Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial [DOI]
- 5 Phase III Study of Fluorouracil, Leucovorin, and Levamisole in High-Risk Stage II and III Colon Cancer: Final Report of Intergroup 0089 [DOI]
- 6 Parasites as negative regulators of cancer [DOI]
- 7 CapOX as neoadjuvant chemotherapy for locally advanced operable colon cancer patients: a prospective single-arm phase II trial [DOI]
- 8 Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer [DOI]
- 9 Guiding Principles for Cancer Surgery during the COVID-19 Pandemic [DOI]
- 10 Colorectal Cancer Associated with Strongyloides stercoralis Colitis [DOI]
- 11 Allergy and Tumour Outcome after Primary Cancer Therapy [DOI]
Cited by 0
No indexed citations yet.
Related research
- Analysis of the Challenges to Healthcare Access among the Economically Disadvantaged Population during the Movement Control Order for COVID-19 Pandemic in Selangor - Malaysia — shares topic coverage
- Personal Factors and Mental Health of Public School Teachers in Lavezares I District, Division of Northern Samar — shares topic coverage
- Emotional and Behavioral Performance among Adolescents Attending at Outpatient Departments of Bangabandhu Sheikh Mujib Medical University during COVID-19 Pandemic — shares topic coverage
- Exam Anxiety among Medical Students in Dhaka City and Its Associated Factors-A Cross-sectional Study — shares topic coverage
- Persistent Microbial Contaminants in Hawked ‘OGI’ and Public Health Concerns in COVID-19 Era — shares topic coverage
Article metrics
Real usage data collected on this platform.
1
Page views
0
PDF downloads
5
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.