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Research Article Open access CC BY 4.0

Comparative Efficacy of Four Fruit Extract Mouthrinses on Gingivitis in Orthodontic Patients : A Randomised Clinical Trial

Asmita Kharche, Swapnil Kurhade, Priyadarshini Sarkate, Mugdha khond, Ganesh Kotalwar, Akshay Gelda

Journal of Pharmaceutical Research International · pp. 268–274 · Published 18 Aug 2021

10.9734/jpri/2021/v33i41A32326

Abstract

Aim: To evaluate the efficacy and antimicrobial properties of four herbal mouthrinses on orthodontic patients with gingivitis Methods and Materials: A total of 60  individuals with fixed orthodontic therapy with established gingivitis were enrolled in this study. Well Diffusion method was used to formulate mouthrinses of freshly prepared fruit extracts from Punica granatum (Pomegranate), Vaccinium macrocarpon (cranberry), Morinda Citrofilia L. (Noni) and Psidium guajava L. (Guava) and distilled water as control. The Plaque and Gingival Index scores were taken into consideration for assessing the effectiveness of mouthrinses against gingivitis. Results: ANOVA test showed significant difference between the groups for PI and GI score (p<0.05). The Post Hoc analysis shows the plaque and gingival  index scores were significantly reduced in Group A ,Group B , Group C and Group D than Group E whereas no significant difference exist in the mean PI  and GI scores of Group A,B,C and D  (p>0.005). Conclusion: All the tested mouthrinses from fruit extract  were equally effective in reducing gingivitis in individuals with fixed orthodontic theraoy suggesting that phytotherapeutic agents may be used  in the future to inhibit oral microbial growth.

phytotherapeutic agent dental plaque gingivitis orthodontic appliances

Cited by 1

Exploring the Benefits of Cranberries in Dentistry: A Comprehensive Review

I. Manso, Yasmim Guterres Bauer, Eduarda Blasi Magini · Biomedicines · 2025

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