Skip to content
Research Article Open access CC BY 4.0

Curbing the Challenges in Recent Treatment Guideline for Early Management of Individuals with Traumatic Spinal Cord Injury: Recommendation for Therapeutic Hypothermia

Stephen Sunday Ede, Chigozie Ikenna Uchenwoke, Kayode Israel Oke, Chigozie Okwudili Obaseki, Franklin Onyedinma Irem

Annual Research & Review in Biology · pp. 1–32 · Published 2 Nov 2020

10.9734/arrb/2020/v35i1130296

Abstract

Background: There has been little prognosis in improving function after a complete spinal lesion. The viewpoint that little can be done to improve motor function after complete SCI seems conceptually and scientifically part of the past. With advance in medicine, better neurological outcome is long expected. Objectives: The purpose of this review is to explore the challenges in recent treatment guidelines’ for early management of patient with TSCI and to draw recommendation for Therapeutic hypothermia. Methods: We conducted a scoping study review comprising 28 studies (2010 to 2020) to identify and examine the research literature related to challenges’ in recent treatment guidelines’ for early management of patient with TSCI. Findings: 28 studies were reviewed. Most cited challenges were surgical timing (26%), followed by controversy on the application of MPS (28.6%). In each of the studies, various challenges of acute stage interventions were outline with poor common standards and recommendations for clinical practices. Surgical decompression (16 papers) was the most cited intervention. Generally, result showed that despite the progress that has been made in the acute management of patients with SCI, neurological outcomes have not improved significantly in recent decades. Conclusion: Key early interventions are increasingly being recognized; combined Neuroprotective and neuroregenerative care are probably more effective and they inspire current and future research. We concluded that an evidence based guidelines for TH would help reduce the doom experience around complete SCIs. Thus there is a need to better define the beneficial effect of TH on the injured SCI.

Traumatic spinal cord injury emergency care treatment guideline therapeutic hypothermia.

References (49)

  1. 1 Scoping studies: towards a methodological framework [DOI]
  2. 2 Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms [DOI]
  3. 3 Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms [DOI]
  4. 4 Early versus Delayed Decompression for Traumatic Cervical Spinal Cord Injury: Results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS) [DOI]
  5. 5 Global prevalence and incidence of traumatic spinal cord injury [DOI]
  6. 6 Writing Usable Qualitative Health Research Findings [DOI]
  7. 7 Timing of Decompressive Surgery of Spinal Cord after Traumatic Spinal Cord Injury: An Evidence-Based Examination of Pre-Clinical and Clinical Studies [DOI]
  8. 8 A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury and Central Cord Syndrome: Recommendations on the Timing (≤24 Hours Versus >24 Hours) of Decompressive Surgery [DOI]
  9. 9 Characterization of Vascular Disruption and Blood–Spinal Cord Barrier Permeability following Traumatic Spinal Cord Injury [DOI]
  10. 10 The Role of Magnetic Resonance Imaging in the Management of Acute Spinal Cord Injury [DOI]
  11. 11 The Influence of Time from Injury to Surgery on Motor Recovery and Length of Hospital Stay in Acute Traumatic Spinal Cord Injury: An Observational Canadian Cohort Study [DOI]
  12. 12 A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Use of Methylprednisolone Sodium Succinate [DOI]
  13. 13 Emerging therapies for acute traumatic spinal cord injury [DOI]
  14. 14 Traumatic spinal cord injury: current concepts and treatment update [DOI]
  15. 15 Prehospital Use of Cervical Collars in Trauma Patients: A Critical Review [DOI]
  16. 16 Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Systematic Review and Meta-Analysis [DOI]
  17. 17 Timing of Decompression in Patients With Acute Spinal Cord Injury: A Systematic Review [DOI]
  18. 18 Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Propensity Score-Matched Cohort Study from a Canadian Multi-Center Spinal Cord Injury Registry [DOI]
  19. 19 Diagnosis and Prognosis of Traumatic Spinal Cord Injury [DOI]
  20. 20 The challenge of spinal cord injury care in the developing world [DOI]
  21. 21 Muscle, Skin and Core Temperature after −110°C Cold Air and 8°C Water Treatment [DOI]
  22. 22 Update on critical care for acute spinal cord injury in the setting of polytrauma [DOI]
  23. 23 A systematic review of the evidence supporting a role for vasopressor support in acute SCI [DOI]
  24. 24 Early acute management in adults with spinal cord injury: a clinical practice guideline for health-care professionals. [DOI]
  25. 25 The Norwegian guidelines for the prehospital management of adult trauma patients with potential spinal injury [DOI]
  26. 26 A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Role of Baseline Magnetic Resonance Imaging in Clinical Decision Making and Outcome Prediction [DOI]
  27. 27 A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Type and Timing of Rehabilitation [DOI]
  28. 28 Recovery following complete paraplegia.
  29. 29 Overview of Therapeutic Hypothermia [DOI]
  30. 30 Routine spinal immobilization in trauma patients: What are the advantages and disadvantages? [DOI]
  31. 31 Acute management of traumatic cervical spinal cord injury [DOI]
  32. 32 Spinal cord injury—The role of surgical treatment for neurological improvement [DOI]
  33. 33 Transportation of Patients With Acute Traumatic Cervical Spine Injuries [DOI]
  34. 34 Evaluation and Management of Acute Cervical Spine Trauma [DOI]
  35. 35 Changes in the Use of the Methylprednisolone Protocol for Traumatic Spinal Cord Injury in Switzerland [DOI]
  36. 36 Therapeutic Hypothermia Improves Hind Limb Motor Outcome and Attenuates Oxidative Stress and Neuronal Damage in the Lumbar Spinal Cord Following Cardiac Arrest [DOI]
  37. 37 M AXIMIZING C OMFORT AND M INIMIZING I SCHEMIA : A C OMPARISON OF F OUR M ETHODS OF S PINAL I MMOBILIZATION [DOI]
  38. 38 Initial management of acute spinal cord injury [DOI]
  39. 39 Therapeutic Hypothermia for Acute Neurological Injuries [DOI]
  40. 40 Current therapeutic strategies for inflammation following traumatic spinal cord injury. [DOI]
  41. 41 Analysis of prehospital care and emergency room treatment of patients with acute traumatic spinal cord injury: a retrospective cohort study on the implementation of current guidelines [DOI]
  42. 42 Effects of cryotherapy methods on circulatory, metabolic, inflammatory and neural properties: a systematic review [DOI]
  43. 43 Controversies in the Surgical Management of Spinal Cord Injuries [DOI]
  44. 44 Early neurological care of patients with spinal cord injury [DOI]
  45. 45 Therapeutic hypothermia: the rationale [DOI]
  46. 46 STUDIES UPON THE TEMPERATURE COEFFICIENT OF THE RATE OF HEART BEAT IN CERTAIN LIVING ANIMALS [DOI]
  47. 47 Pre-hospital and acute management of traumatic spinal cord injury in the Netherlands: survey results urge the need for standardisation [DOI]
  48. 48 Socio-demographic correlates of quality of life in spinal cord injured patients [DOI]
  49. 49 Considerations for Spinal Cord Injury in the Athlete [DOI]

Cited by 0

No indexed citations yet.

Article metrics

Real usage data collected on this platform.

63

Page views

0

PDF downloads

15

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.