Deep Brain Stimulation-Emerging Indications and Newer Techniques: A Current Perspective
Fayrouz Moidu, Sujith Ovallath
International Neuropsychiatric Disease Journal · pp. 53–64 · Published 26 Dec 2022
10.9734/indj/2022/v18i3356Abstract
Deep brain stimulation (DBS) is in clinical use for more than three decades and its indications are ever expanding. Conventionally DBS is used in the treatment of Parkinson’s disease (PD), tremor and dystonia, and has been approved by FDA. It has been tried in several other indications with encouraging results. Recently a DBS device has been approved for use in intractable epilepsy. DBS is giving promising results for use in obesity, trigeminal vascular cephalalgias, and Tourette syndrome and post stroke rehabilitation. Many psychiatric conditions like depression, obsessive compulsive disorder, anorexia nervosa and substance abuse can be controlled with DBS when conventional medical treatment fails to relieve the symptoms. Newer techniques in DBS like directional leads, variable frequency stimulation, newer target identifications, Newer MRI compatible devices, remote programming, newer DBS recording electrodes that can be used in finding out the pathophysiology of disease is also discussed.
References (55)
- 1 Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy [DOI]
- 2 Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus [DOI]
- 3 Combined (Thalamotomy and Stimulation) Stereotactic Surgery of the VIM Thalamic Nucleus for Bilateral Parkinson Disease [DOI]
- 4 Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression [DOI]
- 5 Pallidal Deep-Brain Stimulation in Primary Generalized or Segmental Dystonia [DOI]
- 6 Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Treatment-Resistant Depression [DOI]
- 7 Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression [DOI]
- 8 Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy [DOI]
- 9 A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease [DOI]
- 10 Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease [DOI]
- 11 Memory Enhancement and Deep-Brain Stimulation of the Entorhinal Area [DOI]
- 12 A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer’s Disease [DOI]
- 13 Subcallosal cingulate deep brain stimulation for treatment-refractory anorexia nervosa: a phase 1 pilot trial [DOI]
- 14 Primary Dystonia Is More Responsive than Secondary Dystonia to Pallidal Interventions: Outcome after Pallidotomy or Pallidal Deep Brain Stimulation [DOI]
- 15 Eight-hours adaptive deep brain stimulation in patients with Parkinson disease [DOI]
- 16 Subthalamic nucleus deep brain stimulation in primary cervical dystonia [DOI]
- 17 Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome [DOI]
- 18 Outcome predictors of pallidal stimulation in patients with primary dystonia: the role of disease duration [DOI]
- 19 Deep Brain Stimulation Influences Brain Structure in Alzheimer's Disease [DOI]
- 20 Anatomy, physiology, and pathophysiology of the pedunculopontine nucleus [DOI]
- 21 Low-frequency stimulation of STN-DBS reduces aspiration and freezing of gait in patients with PD [DOI]
- 22 Deep brain stimulation of the subcallosal cingulate for treatment-refractory anorexia nervosa: 1 year follow-up of an open-label trial [DOI]
- 23 Cognitive improvement after long-term electrical stimulation of bilateral anterior thalamic nucleus in refractory epilepsy patients [DOI]
- 24 Deep Brain Stimulation in the Treatment of Obsessive-Compulsive Disorder [DOI]
- 25 Variability and anatomical specificity of the orbitofrontothalamic fibers of passage in the ventral capsule/ventral striatum (VC/VS): precision care for patient-specific tractography-guided targeting of deep brain stimulation (DBS) in obsessive compulsive disorder (OCD) [DOI]
- 26 Neurosurgery clinics of North America [DOI]
- 27 Subthalamic nucleus deep brain stimulation for severe idiopathic dystonia: impact on severity, neuropsychological status, and quality of life [DOI]
- 28 Safety and Tolerability of Donepezil, Rivastigmine and Galantamine for Patients with Alzheimer’s Disease: Systematic Review of the ‘Real-World’ Evidence [DOI]
- 29 Deep brain stimulation in headache [DOI]
- 30 Stereotaxic stimulation and electrocoagulation of the lateral hypothalamus in obese humans [DOI]
- 31 Safety considerations for deep brain stimulation: review and analysis [DOI]
- 32 Chronic electrical stimulation of the contralesional lateral cerebellar nucleus enhances recovery of motor function after cerebral ischemia in rats [DOI]
- 33 Deep brain stimulation of the ventral intermediate nucleus in patients with essential tremor: Stimulation below intercommissural line is more efficient but equally effective as stimulation above [DOI]
- 34 Pallidal stimulation in cervical dystonia: clinical implications of acute changes in stimulation parameters [DOI]
- 35 Deep brain stimulation for torsion dystonia in children [DOI]
- 36 Chronic 30-Hz Deep Cerebellar Stimulation Coupled With Training Enhances Post-ischemia Motor Recovery and Peri-infarct Synaptophysin Expression in Rodents [DOI]
- 37 Nucleus accumbens stimulation in pathological obesity [DOI]
- 38 Automatic Sleep Stage Classification Based on Subthalamic Local Field Potentials [DOI]
- 39 Post subthalamic area deep brain stimulation for tremors: a mini-review [DOI]
- 40 Cortico-striatal circuits: Novel therapeutic targets for substance use disorders [DOI]
- 41 Deep brain stimulation of the lateral cerebellar nucleus produces frequency-specific alterations in motor evoked potentials in the rat in vivo [DOI]
- 42 Variable frequency stimulation of subthalamic nucleus in Parkinson's disease: Rationale and hypothesis [DOI]
- 43 A meta-analysis of the pedunculopontine nucleus deep-brain stimulation effects on Parkinson’s disease [DOI]
- 44 The hypothalamic control of food intake in rats [DOI]
- 45 Effect of stimulation frequency on tremor suppression in essential tremor [DOI]
- 46 Memory Enhancement and Deep-Brain Stimulation of the Entorhinal Area [DOI]
- 47 A Phase I Trial of Deep Brain Stimulation of Memory Circuits in Alzheimer's Disease [DOI]
- 48 Deep Brain Stimulation for Treatment of Tremor [DOI]
- 49 Deep Brain Stimulation for Essential Tremor [DOI]
- 50 [Deep brain stimulation of the ventral intermediate thalamic nucleus in the treatment of essential tremor].
- 51 Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits [DOI]
- 52 Effectiveness of Physiotherapy on Freezing of Gait in Parkinson's Disease: A Systematic Review and Meta‐Analyses [DOI]
- 53 Deep Brain Stimulation for Psychiatric Disorders [DOI]
- 54 Predictive factors for long-term clinical outcomes of deep brain stimulation in the treatment of primary Meige syndrome [DOI]
- 55 Reply: Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome [DOI]
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