Development of a Robust Method for Screening PDE-5 Inhibitor Additives in Dietary Supplements Using UPLC-MS/MS

References (33)

1. 1 A critical review on the use of modern sophisticated hyphenated tools in the characterization of impurities and degradation products [DOI]
2. 2 Oral Phosphodiesterase-5 Inhibitors and Hormonal Treatments for Erectile Dysfunction: A Systematic Review and Meta-analysis [DOI]
3. 3 Phosphodiesterase 5 (PDE5): Structure-function regulation and therapeutic applications of inhibitors [DOI]
4. 4 Therapeutic drug monitoring and LC–MS/MS [DOI]
5. 5 Screening of synthetic PDE-5 inhibitors and their analogues as adulterants: Analytical techniques and challenges [DOI]
6. 6 Phosphodiesterase‐5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition [DOI]
7. 7 Use of liquid chromatography–mass spectrometry and a hydrolytic technique for the detection and structure elucidation of a novel synthetic vardenafil designer drug added illegally to a “natural” herbal dietary supplement [DOI]
8. 8 Adulteration of herbal sexual enhancers and slimmers: The wish for better sexual well-being and perfect body can be risky [DOI]
9. 9 Multiresidue Pesticide Analysis in Fresh Produce by Capillary Gas Chromatography−Mass Spectrometry/Selective Ion Monitoring (GC-MS/SIM) and −Tandem Mass Spectrometry (GC-MS/MS)† [DOI]
10. 10 Accurate mass measurement using Fourier transform ion cyclotron resonance mass spectrometry for structure elucidation of designer drug analogs of tadalafil, vardenafil and sildenafil in herbal and pharmaceutical matrices [DOI]
11. 11 Vision Disorders and Phosphodiesterase Type 5 Inhibitors [DOI]
12. 12 Selective phosphodiesterase-5 (PDE-5) inhibitor vardenafil ameliorates renal damage in type 1 diabetic rats by restoring cyclic 3′,5′ guanosine monophosphate (cGMP) level in podocytes [DOI]
13. 13 Development and validation of a ultra-high-performance liquid chromatography-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines [DOI]
14. 14 Qualitative and quantitative analysis of PDE-5 inhibitors in counterfeit medicines and dietary supplements by HPLC–UV using sildenafil as a sole reference [DOI]
15. 15 Monitoring by LC-MS/MS of 48 compounds of sildenafil, tadalafil, vardenafil and their analogues in illicit health food products in the Korean market advertised as enhancing male sexual performance [DOI]
16. 16 Analysis of phosphodiesterase type 5 inhibitors as possible adulterants of botanical-based dietary supplements: extensive survey of preparations available at the Czech market [DOI]
17. 17 Phosphodiesterase type 5 inhibitors and kidney disease [DOI]
18. 18 Characterization of Sildenafil analogs by MS/MS and NMR: A guidance for detection and structure elucidation of phosphodiesterase-5 inhibitors [DOI]
19. 19 The efficacy of PDE5 inhibitors in diabetic patients [DOI]
20. 20 LC-MS/MS method for the quantitation of serum tocilizumab in rheumatoid arthritis patients using rapid tryptic digestion without IgG purification [DOI]
21. 21 Advanced hydrogels: New expectation for the repair of organic erectile dysfunction [DOI]
22. 22 Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market, 2014–16 [DOI]
23. 23 Multiple Reaction Monitoring with Multistage Fragmentation (MRM3) Detection Enhances Selectivity for LC-MS/MS Analysis of Plasma Free Metanephrines [DOI]
24. 24 Reliable screening and classification of phosphodiesterase type 5 inhibitors in dietary supplements using gas chromatography / mass spectrometry combined with specific common ions [DOI]
25. 25 Determination of Analogs of Sildenafil and Vardenafil in Foods by Column Liquid Chromatography with a Photodiode Array Detector, Mass Spectrometry, and Nuclear Magnetic Resonance Spectrometry [DOI]
26. 26 Structural elucidation of a PDE-5 inhibitor detected as an adulterant in a health supplement [DOI]
27. 27 Development and validation of an ultra-high performance liquid chromatography-high resolution mass spectrometry method for simultaneous quantification of cyanogenic glycosides and secoisolariciresinol diglucoside in flaxseed (Linum usitatissimum L.) [DOI]
28. 28 Single Analyzer Neutral Loss Scans in a Linear Quadrupole Ion Trap Using Orthogonal Double Resonance Excitation [DOI]
29. 29 The paradigm shifting role of chromatographic methods in pharmaceutical analysis [DOI]
30. 30 Screening of Phosphodiesterase-5 Inhibitors and Their Analogs in Dietary Supplements by Liquid Chromatography–Hybrid Ion Trap–Time of Flight Mass Spectrometry [DOI]
31. 31 Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets [DOI]
32. 32 Dispersive magnetic solid-phase extraction for synthetic PDE-5 inhibitors determination by high-performance liquid chromatography with tandem mass spectrometry [DOI]
33. 33 Determination of the PDE-5 Inhibitors and Their Analogues by GC-MS and TMS Derivatization [DOI]

Cited by 0

No indexed citations yet.

Related research

• The Nutraceuticals: A Voluminous Torrent in Pharmaceuticals-coupling Health & Drugs — shares topic coverage
• The Effect of Dietary Supplement on Glutathione Level in Rats — shares topic coverage
• Holistic Treatment of Functional Irritable Bowel Syndrome with a Spotlight on Medical Acupuncture: A Narrative Clinical Update! — shares topic coverage
• Prevalence of Supplement Use and Consumption Practices among the Gym-going Population of Nepal — shares topic coverage
• Awareness about Dietary Supplement Consumption among Student Population — shares topic coverage