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Research Article Open access CC BY 4.0

Diagnosis of Sero-negative Rheumatoid Arthritis Depending on Pathology Associated with Clinical Picture

Aliaa Mamdouh Farag, Noha Elanwar, Mervat Elsergany, Ali Eldeeb, Elham Kassem

Journal of Advances in Medicine and Medical Research · pp. 88–93 · Published 13 Jun 2023

10.9734/jammr/2023/v35i155082

Abstract

Objectives: This study was done to assess the role of synovial tissue analysis in rheumatoid arthritis (RA) patients. Methods: All data were recorded at baseline. All patients underwent clinical, radiologic, serologic, and histological assessments before treatment. Patients were divided into anti-citrullinated protein antibody (anti-CCP) positive and anti-CCP-negative and were compared according to different disease aspects. Correlations between clinical, laboratory, imaging, histological, and pathophysiological data were done for all patients. Results: There were no statistically significant differences in synovial cell infiltrates according to the serology. Conclusion: Both study groups had similar synovial cell infiltrates.

Arthritis rheumatoid synovial tissue synovitis

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