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Research Article Open access CC BY 4.0

Disease of the Thyroid Gland: A Histopathological Perspective

Innocent Emmanuel, Mansur Ramalan Aliyu, Adam Ochigbo, Philip Akpa, Jagshak Barnabas Mandong, Barnabas Mafala Mandong

Asian Journal of Research and Reports in Endocrinology · pp. 32–40 · Published 12 Mar 2019

10.9734/ajrre/2018/v1i110

Abstract

The thyroid is affected primarily by disease conditions which are variously classified and are not uncommon worldwide. They could lead to enlargement of the thyroid gland thereby earning the designation “goiter”. Globally, iodine deficiency has been identified as a major cause of goiter. This was a descriptive retrospective study of consecutive cases of thyroid specimen analyzed at the Histopathology Department of the Jos University Teaching Hospital, Jos, Nigeria, between January 2008 and December 2017. The aim of this work is to study thyroid disorders histologically, relating these findings to age and sex, and comparing same with previous reports. The Hospital’s Medical records and the Histopathology Departments served as sources for extraction of patient’s data which included age, sex, and histological diagnosis. Archival slides were reviewed to confirm the diagnosis of the thyroid lesion. Three hundred and eleven (311) cases of thyroid disease were diagnosed histologically at the Jos University Teaching Hospital during the study period. These lesions were broadly classified into developmental anomalies, hyperplasias, immune/inflammatory diseases, and neoplasm. They accounted for 1.9% (6 cases), 81.3% (253 cases), 3.9% (12 cases), and 12.9% (40 cases) of all cases respectively. The age range of the study population was 1 year to 70 years, with a mean age of 41.2±12.0 SD, and peak incidence at 30 years to 39 years. There were 25 males and 286 females making a male female (M/F) ratio of 1:10.2. Thyroid disorders are essentially a female disease in our environment occurring commonly in the third and fourth decade of life.

Goiter iodine Jos.

References (25)

  1. 1 1969 Cancer Facts and Figures [DOI]
  2. 2 Global Iodine Nutrition: Where Do We Stand in 2013? [DOI]
  3. 3 Role of Iodine, Selenium and Other Micronutrients in Thyroid Function and Disorders [DOI]
  4. 4 Factors Associated with the Prevalence of Thyroid Nodules and Goiter in Middle-Aged Euthyroid Subjects [DOI]
  5. 5 Endemic goiter associated with high iodine intake [DOI]
  6. 6 Prevalence of Goiter and Thyroid Nodules before and after Implementation of the Universal Salt Iodization Program in Mainland China from 1985 to 2014: A Systematic Review and Meta-Analysis [DOI]
  7. 7 Effects of Chronic Iodine Excess in a Cohort of Long-Term American Workers in West Africa [DOI]
  8. 8 Persistence of severe iodine-deficiency disorders despite universal salt iodization in an iodine-deficient area in northern India [DOI]
  9. 9 Spectrum and prevalence of thyroid diseases seen at a tertiary health facility in Sagamu, South-West Nigeria [DOI]
  10. 10 Thyroid cancer and thyroiditis in the goitrous region of Salta, Argentina, before and after iodine prophylaxis [DOI]
  11. 11 The relative roles of endemic goiter and socioeconomic development status in the prognosis of thyroid carcinoma [DOI]
  12. 12 Thyroid carcinoma at King Edward VIII Hospital, Durban, South Africa [DOI]
  13. 13 Impact of Iodination on Thyroid Pathology in Africa [DOI]
  14. 14 The Standard, Intervention Measures and Health Risk for High Water Iodine Areas [DOI]
  15. 15 Histopathological pattern of thyroid lesions in Kano, Nigeria: A 10-year retrospective review (2002-2011) [DOI]
  16. 16 Thyroid cancers in Ibadan, Nigeria.
  17. 17 Histopathological pattern of malignancy in solitary thyroid nodule [DOI]
  18. 18 Goitre and thyroid cancer [DOI]
  19. 19 Thyroid Disorders in Accra, Ghana: A Retrospective Histopathological Study at the Korle-Bu Teaching Hospital
  20. 20 Histopathological pattern of thyroid diseases in Zaria: A 10-year review [DOI]
  21. 21 Vitamin E ameliorates iodine-induced cytotoxicity in thyroid [DOI]
  22. 22 Thyroid cancer in Pacific women in New Zealand.
  23. 23 Study of histopathological pattern of thyroid lesions [DOI]
  24. 24 An analysis of thyroid diseases seen at Kenyatta National Hospital.
  25. 25 Thyroid swellings- A Common Problem in Hilly Areas [DOI]

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