Drug Utilization Pattern and Cost Analysis in Rheumatoid Arthritis Patients – A Cross–Sectional Study in Tertiary Care Hospital, Mumbai
S. R. Gawde, Y. C. Shetty, S Merchant, U. J. Kulkarni, M. Y. Nadkar
Journal of Pharmaceutical Research International · pp. 37–45 · Published 19 Dec 2012
10.9734/BJPR/2013/2229Abstract
Aims: To study the current prescription pattern and to analyze the cost of the treatment Prescribed to RA patients referred to rheumatology OPD in KEM hospital. Study Design: Cross-sectional study. Place and Duration of Study: Department of Medicine and Department of Pharmacology, Seth GSMC & KEM Hospital, between July 2011 and December 2011. Methodology: The study protocol was approved by the institutional ethics committee. Patients attending Rheumatology OPD for existing RA disease were recruited as per inclusion criteria. Written informed consent was sought. It was a cross-sectional study. Total 100 consecutive rheumatoid arthritis patients (fulfilling the American College of Rheumatology Criteria 1987) were recruited from 1st July to 1st September 2011. Results: Majority of patients (67%) in the study population were on combination of two DMARDs. Most frequently prescribed two DMARDs combination was methotrexate and hydroxychloroquine (64%). Average total cost per prescription was found to be 763.39 Indian rupees (US$ 14), while average hospital and out of pocket expense were 281.12 Indian rupees (US$ 5) and 482.88 Indian rupees (US$ 9) respectively. Conclusion: The drug use pattern in RA was found to be DMARDs based and majority of the cost was borne by the patient. The total cost increased was due to administration of drugs to treat the adverse drug reaction. Prospective studies in a larger number of patients are needed to assess the utility of prescription audit and cost analysis of drugs used in RA.
References (9)
- 1 Epidemiology and burden of illness of rheumatoid arthritis [DOI]
- 2 Health-Care Systems and Pharmacoeconomic Research in Asia-Pacific Region [DOI]
- 3 Treatment failure with disease-modifying antirheumatic drugs in rheumatoid arthritis patients.
- 4 Health economics: implications for novel antirheumatic therapies [DOI]
- 5 Generic Substitution Issues: Brand-generic Substitution, Generic-generic Substitution, and Generic Substitution of Narrow Therapeutic Index (NTI)/Critical Dose Drugs.
- 6 Thoughts on health economics in rheumatoid arthritis [DOI]
- 7 Cost evaluation of novel therapeutics in rheumatoid arthritis (CENTRA):A decision analysis model [DOI]
- 8 Treatment and monitoring costs in rheumatoid arthritis: Preliminary results from an Indian setting [DOI]
- 9 The total costs of drug therapy for rheumatoid arthritis [DOI]
Cited by 24
Vikas Yadav, Sanjay Jaiswal, Sharan Shyam · Journal of Current Research in Scientific Medicine · 2022
Satish Kumar, Ankit Kumar, A. S. Menon · Medical Journal of Dr. D.Y. Patil Vidyapeeth · 2024
Ashit Syngle, Sudeep Kaur, Inderjeet Verma · Clinical Rheumatology · 2017
R Joshi, B Medhi, A Prakash · Indian Journal of Pharmacology · 2022
Gauri Mittal, Manisha Bisht, Venkatesh S Pai · Cureus · 2023
BhupinderS Kalra, Angelika Batta, Nikita Madan · MAMC Journal of Medical Sciences · 2019
Gauri Mittal, Manisha Bisht, Venkatesh S. Pai · Journal of Family Medicine and Primary Care · 2021
J Narendra Varma, E. Satheesh Kumar, Asna Subair · Indian Journal of Pharmacy and Pharmacology · 2024
A. Riyaz Siddiqui, Shadma Quazi, Sharjeel Khan · Journal of Datta Meghe Institute of Medical Sciences University · 2023
Showing 9 of 24 known citations — external sources report more than can currently be individually listed.
Related research
- Long-term Observation of the Serum Level of Anti-influenza Antibody Titers in Patients with Rheumatoid Arthritis on Receiving Vaccination with Identical Strains in the 2010 to 2012 Season — shares topic coverage
- Assessment of Formaldehyde-Induced Arthritis (FIA) using Modified Rheumatoid Arthritis Disease Activity Index (RADAI) on Adult Male Wistar Rats — shares topic coverage
- Adipocytokines, Receptor Activator of Nuclear Factor-κB Ligand, and Midkine: Intricate Biomarkers Network Involved in Pathogenesis and Activity of Rheumatoid Arthritis in Egyptians — shares topic coverage
- Assessment of Autoimmune and Inflammatory Biomarkers in Rheumatoid Arthritis Subjects in Port Harcourt, Nigeria — shares topic coverage
- Ocular Reactions during Chronic Inflammatory Rheumatisms — shares topic coverage
Article metrics
Real usage data collected on this platform.
21
Page views
0
PDF downloads
4
Outbound clicks
24
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.