Effect of Zinc Oxide Nanoparticles on Some Production Qualities and Biochemical Parameters of Broiler Chickens

Abstract

The goal of this study was to determine the effects of dietary zinc oxide nanoparticles (ZnO-NPs) on the metabolic, antioxidant, and productive parameters of broilers. Zinc oxide nanoparticles were prepared using from black raisins without seeds. Zinc oxide nanoparticles (ZnO NPs) are considered an advanced poultry feed additive, surpassing traditional zinc in absorption efficiency thanks to their small size and large surface area. Their key benefits include improved growth rates and feed conversion efficiency, enhanced immunity, reduced oxidative stress, and potent antibacterial action that regulates gut microbiota, thus decreasing the need for antibiotics. Two hundred one-day-old broiler chicks were purchased from a local market and randomly distributed into four groups of 50 birds each. into four groups of 50 birds each group (a control group and three treatment groups supplemented with ZnO-NPs at 50, 75, and 100 mg/kg of feed), and were raised for 35  days. Feed intake (FI), body weight (BW), feed conversion ratio (FCR), and mortality rate (MR) were measured. At the end of the experiment, Blood was drawn to assess kidney function (uric acid, UA; creatinine, Cr), liver function (alanine aminotransferase, ALT; aspartate aminotransferase, AST), lipid profile..." (This whole section needs reordering for clarity). total plasma protein (TP), globulin (GL), total cholesterol (T-Ch), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL)." total antioxidant capacity (TAOC), glutathione peroxidase (GPx), superoxide dismutase (SOD), and malondialdehyde (MDA), The results showed a significant increase (P < 0.05) in body weight, feed conversion efficiency, and antioxidant levels, along with higher total protein and globulin, and lower total cholesterol, triglycerides, urea, creatinine, and liver enzymes compared to the control group." (Note: "less perishables" is incorrect; "lower mortality" is meant), total protein and globulin with low total cholesterol and fat. Triglyceride, urea, creatinine and liver enzymes were compared to the control group and There was no significant difference (P > 0.05) between the 50 and 75 mg/kg groups." (Using P<0.0001 here is contradictory). The best results were when zinc oxide nanoparticles were given at a concentration of 100 mg/kg feed. It is concluded that administration of 100 mg/kg of zinc oxide nanoparticles improves the health of birds by increasing weight, antioxidants, nutritional conversion efficiency, and effective liver and kidney activity.