Evaluation of Drug Utilization in Coronary Artery Disease in Tertiary Care Centre: A Cross Sectional Study

Abstract

Aim: In this study, the goal was to asses Drug utilization evaluation, WHO core indicators, monitoring the patient’s response to therapy of coronary artery disease. Study Design:  Sapthagiri institute of medical sciences, Bangalore. Place and Duration of Study: Sample: Department of Cardiology Sapthagiri Institute of Medical Sciences (SIMS), From (June 2024- Nov 2024) Chikkasandra, Hesaraghatta Road Bangalore. Methodology: We conducted prospective cross-sectional study for 6 months which includes patients who were diagnosed with coronary artery disease diagnosed of different types. Results: Among 311 patients, 30.2% were in the age group between 58-67 years of age. By 68.8%, male patients outnumbered female patients. Ischemic heart disease in coronary artery disease were the most common diagnosis. Out of 311 patients, 197 patients had comorbidities and the most common comorbidity was Hypertension (66), Diabetes melitus (47). Most commonly used combination therapy was Coronary angiography (CAG) with drug therapy (233). Majority of drugs prescribed under generic name with Aspirin (244). Category of drugs used is antiplatelet (471). Oral route (1423) of drug administration was the preferred route. Drug interactions are moderate which can be avoided at dose adjustments and limiting to single drug use of antiplatelets. WHO reports 45% of prescriptions include 5.4 drugs, 2.3% prescribe antibiotics, 10.6% use injections, 73.2% use generic names, and 98% are from the essential medicines list. Conclusion: The study evaluated drug utilization in coronary artery disease patients in a tertiary care hospital. The most common treatment approach was Coronary Angiography with drug therapy, with antiplatelet, antihypertensive, and antidiabetic drugs being the most commonly prescribed.