Histopathological Patterns of Thyroid Neoplasms in Ibadan Nigeria: A Twenty Year Retrospective Study
O. O. Ariyibi, B. M. Duduyemi, E. E. Akang, A. O. Oluwasola
International Journal of TROPICAL DISEASE & Health · pp. 148–156 · Published 2 Apr 2013
10.9734/IJTDH/2013/2936Abstract
Background: The thyroid gland is an endocrine organ which has an important function in regulation of physiological functions of normal body metabolism. Thyroid neoplasms are usually presented with palpable solitary or multiple nodules. This retrospective study aimed at describing the histopathological patterns of various thyroid neoplasms at the Pathology Department, University College Hospital (UCH), Ibadan between 1987 and 2006. Methods: We reviewed 174 cases with thyroidectomy and diagnosed thyroid neoplasm. We evaluated heamatoxilin and eosin stained slides retrieved from the records of the department and the population based cancer registry and where necessary the paraffin blocks were recut and stained. The World Health Organization Histological Classification of Thyroid tumour (2004) was used in this study. Results: A total 74,202 biopsies were received in the department over the study period. 1,207 cases were thyroidectomy specimens constituting 1.6% of all biopsies in the study period. 174 cases (14.4%) were thyroid gland neoplasms 122 (70.1%) of which were females and 52 of which (29.9%) were males. The ratio of female to male is 2.3:1. Seventy six (43.7%) cases were benign and 98 (56.3%) cases were malignant. Follicular adenoma accounted for 89.5% of benign thyroid neoplasms which makes a peak in the 5th decade. Papillary carcinoma was the most common malignant thyroid neoplasm in this study with a peak in the 3rd decade. Conclusion: This study showed that thyroid neoplasms were showing female predominance. The most common benign neoplasm was follicular adenoma and the malignant neoplasm was papillary carcinoma.
References (12)
- 1 The National Comprehensive Cancer Network [DOI]
- 2 Metastatic tumors of the thyroid gland: a study of 79 cases in Chinese patients.
- 3 Thyroid carcinoma at King Edward VIII Hospital, Durban, South Africa [DOI]
- 4 Thyroid cancers in Ibadan, Nigeria.
- 5 Neoplasm of the Thyroid Gland [DOI]
- 6 Solitary thyroid nodule in Khartoum.
- 7 An analysis of thyroid diseases seen at Kenyatta National Hospital.
- 8 Carcinoma of the thyroid in Khartoum.
- 9 Carcinoma of the thyroid at Harare histopathology laboratory (Zimbabwe).
- 10 Histological pattern of thyroid diseases in Enugu, Nigeria.
- 11 Thyroid neoplasms in Tikur Anbessa Hospital, Addis Ababa: a retrospective review with emphasis on cancer.
- 12 Isolated intrathyroidal metastasis revealing an occult lung adenocarcinoma [DOI]
Cited by 19
Asma Aboubakr Miftah Abdalraziq, Raba M. Abdalkarim, Eman Alaqeli · Tobruk University Journal of Medical Sciences · 2022
Samuel Kelechi Richard, Barka Vandi Kwaghe, Nwadiokwu John Ifeanyi · Nigerian Postgraduate Medical Journal · 2025
Samuel Kelechi Richard, Barka Vandi Kwaghe, Innocent Emmanuel · 2024
Ghina Almustafa, Masa Bytamoni, Imad-Addin Almasri · 2024
Khulaif Alanazi, Laila Seada, Salman Harbi · International Journal of Medicine in Developing Countries · 2021
Showing 5 of 19 known citations — external sources report more than can currently be individually listed.
Related research
- Ear Diseases among Primary School Children in Ibadan Metropolis, Southwestern Nigeria — shares topic coverage
- Evaluation of Potassium Bromate in Bread in Ibadan Metropolis: Fifteen Years after Ban in Nigeria — shares topic coverage
- Antibiotic Sensitivity Profiles of Salmonella typhimurium and E. coli O157: H7 Isolates from Ready to Eat Chicken Meat in Ibadan-Nigeria — shares topic coverage
- Serological Markers of Hepatitis B Virus Infectivity among Hepatitis B Surface Antigen Negative Blood Donors at the University College Hospital, Ibadan — shares topic coverage
- Determination of Pb in Ibadan Metropolis —An Indication of Environmental Pollution — shares topic coverage
Article metrics
Real usage data collected on this platform.
55
Page views
0
PDF downloads
9
Outbound clicks
19
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.