Hyperinsulinemia and Preeclampsia among Pregnant Women: A Quantitative Study

Abstract

Hypertensive disorders in pregnancy complicate 1 in 10 pregnancies, often associated with maternal and neonatal mortality and morbidity. The study was done on 100 pregnant women’s attending antenatal clinic of SreeBalaji Medical College & Hospital, Chromepet, Chennai, during the period from December 2013 - May 2015. All women who met the inclusion and exclusion criteria were taken intothe study. Fasting insulin was calculated at 18 -22weeks of gestation, and then follow up of caseswas donefor signs of development of Pregnancy-induced hypertension (PIH). In the hypertensive group, the bulk of the patients were between the ages of 25 and 30. As (P > 0.05), there is no statistical Significance in correlation between age and (PIH) in our study. Out of 100 cases studied, 64 cases (64%) had hyperinsulinemia. The remaining 36 cases (36%) had normal insulin values. The prevalence of PIH associated with hyperinsulinemia was 58% in our study. This test showed sensitivity of 87%, specificity of 82%, positive predictive value of 90%, negative predictive value 77% and diagnostic accuracy was 92%.