Ischemic Stroke in COVID-19: A Systematic Review
Ganna Trepet, Nataliia Radzikhovska
Journal of Pharmaceutical Research International · pp. 2412–2420 · Published 26 Dec 2021
10.9734/jpri/2021/v33i60B34893Abstract
Aims: To determine an association between inflammatory and coagulation markers in a COVID-19 patient with ischemic stroke. Study Design: We performed a systematic review of 4 databases using the keywords “ischemic”, “stroke”, “COVID-19”,” Virus” Place and Duration of Study: December 2021 - January 2022. Methodology: Randomised control trials, observational studies, and systematic reviews were evaluated to ascertain the correlation between inflammatory and coagulation markers in COVID-19 patients with Ischemic stroke. Searches were conducted using Cochrane/EMBASE, PubMed/Medline, and PEDro between (2020-2021). Results: Of the inflammatory markers, white blood cells (WBC) and platelets did not vary considerably outside their normal ranges. All markers of hypercoagulability were elevated, but only Prothrombin Time corresponded with C-reactive protein (CRP). Conclusion: Inflammatory markers were not useful in forecasting the development of acute ischemic stroke, but CRP levels may be a possible marker to further research. D-dimer is a tried and true lab test that should be part of management guidelines in the ongoing COVID pandemic.
Cited by 1
Any Axelerad, Lavinia-Florenta Muja, Alina Zorina Stuparu · ARS Medica Tomitana · 2023
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