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Research Article Open access CC BY 4.0

Knowledge, Attitude and Practice Regarding Antibiotic Use and Self- Medication in MBBS Students: A Cross-Sectional Study

Panchal Ripal Nandlal, Galachar Hiral Lakhabhai

Journal of Pharmaceutical Research International · pp. 70–81 · Published 24 Apr 2026

10.9734/jpri/2026/v38i47833

Abstract

Background: Antibiotic misuse and self-medication contribute significantly to antimicrobial resistance (AMR), a major global health threat. Medical students, despite their education, often engage in self- medication with antibiotics, highlighting a concerning gap between knowledge and practice. Aim: The study aims to assess the knowledge, attitude, and practice (KAP) regarding antibiotic use and self-medication among MBBS students using a cross-sectional study method. Methods: A cross-sectional, questionnaire-based study was conducted among MBBS students in Gujarat. Data were collected via Google Forms and analyzed using Excel 2021. A chi- square test was performed to analyze gender-based differences in self-medication behavior. Results: Among 210 respondents, 51.4% reported self-medicating with antibiotics. Knowledge levels were high, with over 90% correctly identifying antibiotics and understanding AMR. However, 64.3% obtained antibiotics without prescriptions, and 41% showed reluctance to attend AMR awareness programs. The chi-square test revealed no significant association between gender and self-medication behavior (p = 1.0). Conclusion: Despite high awareness, self-medication remains prevalent among MBBS students, demonstrating a gap between knowledge and responsible behavior. Strengthening pharmacy regulations, integrating behavioral interventions into medical curricula, and promoting responsible antibiotic use are crucial to addressing this issue.

Knowledge attitude and practice (KAP) self-medication MBBS students antibiotic use

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