Lactate Dehydrogenase Enzyme Level in Women with Severe Preeclampsia: A Cross-sectional Study
Nadia Hameed, Yasmeen Bibi, Shehreen Memon, Sanam Channa, Muhammad Ali Memon, Muhammad Nadeem Chohan
Journal of Pharmaceutical Research International · pp. 28–33 · Published 10 Mar 2022
10.9734/jpri/2022/v34i21B35845Abstract
Aim: To determine the frequency of raised lactate dehydrogenase enzyme in women with severe preeclampsia. Study Design: Cross-sectional study. Place and Duration: Obstetrics and Gynecology department at Liaquat University Hospital Hyderabad from June 2018 to December 2018. Methodology: There were 141 primiparous women with severe preeclampsia, included in this study. After taking history regarding hypertension and obstetrical examination, patients were subjected to a relevant investigation that is, 5ml of blood sent to an institutional laboratory for the measurement of lactate dehydrogenase enzyme, if it is >400 U/L then it was labeled as raised. Results: The frequency of raised lactate dehydrogenase enzyme (400 U/L) was 13.48% (19/141) women with severe preeclampsia. Conclusion: About 14% of women having Pre-eclampsia had raised lactate dehydrogenase enzyme. Severe preeclampsia is associated with severe multisystemic involvement. Raised LDH levels are indicative of cellular damage and severe hypertension in pregnancy.
Cited by 2
Saba Shafiq, Muhammad Nadim Akbar Khan, S. Qayyum · JPMA. The Journal of the Pakistan Medical Association · 2024
Bambang Rahardjo, Talita Nandia Primarintan · Asian Journal of Health Research · 2023
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