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Research Article Open access CC BY 4.0

Mallory Weiss Tear - An Uncommon Cause of Upper G.I Bleeding in a Cardiac Patient with Successful Dual Intervention

M. Sumalatha, Kulsoom Fatima, Sethu Babu, Mohammed Sadiq Azam

International Journal of Medical and Pharmaceutical Case Reports · pp. 12–18 · Published 25 Feb 2023

10.9734/ijmpcr/2023/v16i1324

Abstract

Introduction: Primary Percutaneous Coronary Intervention (PPCI) with stenting, especially with Drug eluting stents (DES), is the most widely accepted strategy globally for patients presented with STEMI, which necessitates a long duration of Dual antiplatelet therapy (DAPT) to prevent stent thrombosis. Potent P2Y12 inhibitors for DAPT are preferred in view of their superior protection against thrombosis but at the expense of increased bleeding risks. Early therapeutic intervention in the event of acute GI bleed has beneficial outcome while on active cardiac intervention. Case Presentation: A 67-year-old patient, who underwent PPCI with DES stent, incidentally developed Mallory-Weiss (MW) tear, which manifested as severe hematemesis when loaded with DAPT consisting of Aspirin and Ticagrelor. The therapy was withheld until the clipping of the tear was done. Single antiplatelet therapy (SAPT) with Aspirin was reinstituted after a day and DAPT with Aspirin plus Clopidogrel after a week. Conclusion: A careful assessment of the risks and benefits of acute coronary interventions need to consider complications and timely interventions thus individualizing and curating the DAPT as deemed necessary.

Primary Percutaneous Coronary Intervention (PPCI) Dual Antiplatelet Therapy (DAPT) upper gastrointestinal bleeding Mallory-Weiss tear

References (16)

  1. 1 Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation [DOI]
  2. 2 A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee
  3. 3 Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation [DOI]
  4. 4 High incidence of clopidogrel‐associated gastrointestinal bleeding in patients with previous peptic ulcer disease [DOI]
  5. 5 Comparison of Glasgow-Blatchford Score and Rockall Score in Patients with Upper Gastrointestinal Bleeding [DOI]
  6. 6 Systematic review with meta‐analysis: the risk of gastrointestinal bleeding in patients taking third‐generation P2Y12 inhibitors compared with clopidogrel [DOI]
  7. 7 Gastrointestinal Injury Caused by Aspirin or Clopidogrel Monotherapy Versus Dual Antiplatelet Therapy [DOI]
  8. 8 Bleeding and management of bleeding [DOI]
  9. 9 Optimised care of elderly patients with acute coronary syndrome [DOI]
  10. 10 Dual Antiplatelet Therapy After Drug-eluting Stent Implantation [DOI]
  11. 11 Mallory-Weiss syndrome [DOI]
  12. 12 Mallory-Weiss syndrome. A reappraisal [DOI]
  13. 13 The Evolving Post-PCI Antithrombotic Therapies [DOI]
  14. 14 Upper Gastrointestinal Bleeding [DOI]
  15. 15 Evaluation and Management of Mallory – Weiss Syndrome: A Review [DOI]
  16. 16 Salvage treatment for severe upper gastrointestinal bleeding caused by Mallory-Weiss syndrome and myocardial depression after acute myocardial infarction [DOI]

Cited by 2

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