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Research Article Open access CC BY 4.0

Management of Chemotherapy Induced Mucositis

Ashwag Siddik Noorsaeed, Mawaddah Saad Aljohani, Khawlah Salem A. BinAfif, Rafal Abdulrahman Alsaywed, Maha Ali Bakhshwain, Reham Mohammed Alharbi, Heba Abdulhakeem M. Bukhari, Omar Mohammed Albalushi, Ahmad Abdulrahman Aljuhani, Amal Abdullah Batarfi, Awatif Fakhri Subahi, Azzah Mohammed S Alghamdi, Moyssar tariq khallaf, Zainah Ali Asiri

Journal of Pharmaceutical Research International · pp. 220–226 · Published 17 Dec 2021

10.9734/jpri/2021/v33i59B34372

Abstract

Oral mucositis is a severe ailment that causes erythema, edema, and ulceration of the oral mucosa, as well as pain and oral intake restrictions. Chemotherapy and radiation therapy are the most often utilized cancer treatment options. Despite the fact that these treatments are used to improve a patient's quality of life, they are linked to a number of negative side effects. Oral mucositis is a common side effect in patients undergoing head and neck radiation therapy. While some chemotherapy-related side effects are being better managed, mucositis is becoming more common. Reducing patient risk factors, adopt proven preventative measures, and optimize supportive care practices targeted to the patients' needs and symptoms are all recommendations that can be made. In clinical practice and research, a variety of measures have been used to record the amount and severity of oral mucositis. The World Health Organization (WHO) scale is a simple, easy-to-use scale that can be used in clinical practice on a regular basis. There are multiple approaches for management of Mucositis.  Cryotherapy, palifermin, and sucralfate are among the three therapies that showed statistically significant effect in avoiding or lowering the severity of mucositis according to reports. In this article we’ll be looking at Chemotherapy induced mucositis, its etiology, epidemiology, evaluation. And most importantly management.

Oral mucositis erythema oral mucosa edema epidemiology chemotherapy

Cited by 1

Methotrexate Induced Oral Mucositis and Bone Marrow Suppression in Psoriatic Patient

Aadithya, Raghuveer S Prabhu, Rahmathullah SN · International Journal of Medical and Pharmaceutical Case Reports · 2024

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