Monograph on COVID-19 Vaccines: A Review

Abstract

In this monograph various types of vaccines available in the market and the future of vaccination in relation to COVID-19 will be discussed in detail. The design and production of vaccines to combat SARS-CoV-2 were mostly directed towards the surface exposed spike glycoprotein. Modena (mRNA-1273) COVID-19 vaccine was approved by the Food and Drug Administration (FDA) on 18 Dec 2020 under Emergency Use Authorization (EUA). BNT162b2is a lipid nanoparticle encapsulated, nucleoside modified mRNA vaccine the encodes for the perfusion spike glycoprotein present in SARS-CoV-2. The act of proceeding to approve vaccines before Phase III trials, have installed doubt and vaccine hesitancy. This further impedes the process of vaccination thereby slowing the chance of the entire world getting vaccinated. The only way to protect oneself from being seriously ill and hospitalized is by following social distancing and getting vaccinated as early as possible. Despite, the lack of cold chain storage in certain regions, there are a variety of vaccines available to help negotiate this obstacle. More research and efforts will be poured into COVID-19 pandemic as we work towards a universal vaccine that will be effective against all the variants of SARS-CoV-2 and help eradicate the virus from the face of the earth.