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Research Article Open access CC BY 4.0

Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer

Sonali Suchismita Behera, Seema Suvadarshini, Truptimayee Chhotaray, Archita Sahoo, Subhadarshini Satapathy, Manasi Mohapatra, Bhagyeswari Behera, Srimay Pradhan

Journal of Pharmaceutical Research International · pp. 118–121 · Published 21 Jun 2020

10.9734/jpri/2020/v32i930540

Abstract

Moringa oleifera plant extract is traditionally used to cure Peptic ulcer. It is caused by Helicobacter pylori. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 9-octadecenoic acid can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Phytochemical Moringa oleifera Helicobacter pylori peptic ulcer.

References (2)

  1. 1 The weirdest people in the world? [DOI]
  2. 2 In silico Analysis of Phytochemicals from Mucuna pruriens (L.) DC against Mycobacterium tuberculosis Causing Tuberculosis [DOI]

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