Skip to content
Research Article Open access CC BY 4.0

Nano Emulsion: The Targeted Drug Delivery in the Therapy of Epilepsy

N. V. L. Suvarchala Reddy V., M. Ganga Raju, Keerthana Edunoori, Jyothi Papani

International Research Journal of Pure and Applied Chemistry · pp. 46–53 · Published 2 Sep 2023

10.9734/irjpac/2023/v24i5824

Abstract

Around the world, 50 million people suffer with epilepsy; it significantly burdens society in terms of finances, society, and health. Our comprehension of the pathophysiological processes causing the illness and the factors affecting its prognosis has significantly advanced during the last ten years. Around a third of patients are still resistive to medical intervention, despite the fact that the number of antiepileptic drugs has expanded dramatically over the past 20 years. The ability of nanotech-based anti-epileptic drug (AED) administration methods to cross the blood brain barrier, increase specificity, and have the capacity for extended brain administration of drugs have lately attracted interest. Nanotechnology appears to be a promising and innovative development in this area. Nano emulsions have a mean droplet size of 20 to 200 nm and remain kinetically stable dispersions of two incompatible liquids with the assistance of an emulsifier or emulsifiers. The effectiveness of NEs as a delivery system for Central Nervous System-active medications used in effective regimens against difficult-to-treat CNS conditions.

Epilepsy types of seizures antiepileptic drugs nanoemulsions

References (28)

  1. 1 Nanoemulsions: formation, properties and applications [DOI]
  2. 2 The Epidemiology of Epilepsy [DOI]
  3. 3 The neurobiology of antiepileptic drugs [DOI]
  4. 4 Nanoemulsion: an advanced mode of drug delivery system [DOI]
  5. 5 Techniques for Formulation of Nanoemulsion Drug Delivery System: A Review [DOI]
  6. 6 Current State of Nanoemulsions in Drug Delivery [DOI]
  7. 7 The epidemiology of the epilepsies [DOI]
  8. 8 Nanoemulsion: Promising nanocarrier system for delivery of herbal bioactives [DOI]
  9. 9 Challenges and Future Prospects of Nanoemulsion as a Drug Delivery System [DOI]
  10. 10 Pharmacological and Therapeutic Approaches in the Treatment of Epilepsy [DOI]
  11. 11 Nanoemulsions for targeting the neurodegenerative diseases: Alzheimer's, Parkinson's and Prion's [DOI]
  12. 12 Nanotechnology applications in drug controlled release [DOI]
  13. 13 Design and development of letrozole nanoemulsion: A comparative evaluation of brain targeted nanoemulsion with free letrozole against status epilepticus and neurodegeneration in mice [DOI]
  14. 14 Management of epileptic disorders using nanotechnology-based strategies for nose-to-brain drug delivery [DOI]
  15. 15 Preparation and evaluation of biphenyl dimethyl dicarboxylate microemulsions for oral delivery [DOI]
  16. 16 Intranasal delivery of topiramate nanoemulsion: Pharmacodynamic, pharmacokinetic and brain uptake studies [DOI]
  17. 17 Preparation, Characterization and Applications of Nanoemulsions: An Insight [DOI]
  18. 18 Nanoformulated ellagic acid ameliorates pentylenetetrazol-induced experimental epileptic seizures by modulating oxidative stress, inflammatory cytokines and apoptosis in the brains of male mice [DOI]
  19. 19 RETRACTED ARTICLE: Impact of ultrasonication techniques on the preparation of novel Amiloride-nanoemulsion used for intranasal delivery in the treatment of epilepsy [DOI]
  20. 20 Determination of role of GABA and nitric oxide in anticonvulsant activity of Fragaria vesca L. ethanolic extract in chemically induced epilepsy in laboratory animals [DOI]
  21. 21 Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry [DOI]
  22. 22 Nanoemulsion preparation, characterization, and application in the field of biomedicine [DOI]
  23. 23 Nanoemulsions for drug delivery [DOI]
  24. 24 Development of Nanoemulsion containing Centella Asiatica Crude Extract as a Promising Drug Delivery System for Epilepsy Treatment [DOI]
  25. 25 Nanotechnology-based approaches in diagnosis and treatment of epilepsy [DOI]
  26. 26 The study of antiepileptic activity of clove oil by MES model in mice [DOI]
  27. 27 International Journal of Pharmaceutics
  28. 28 Journal of Drug Delivery and Therapeutics [DOI]

Cited by 4

Nanoemulsions of Cannabidiol, Δ9-Tetrahydrocannabinol, and Their Combination Similarly Exerted Anticonvulsant and Antioxidant Effects in Mice Treated with Pentylenetetrazole

Pedro de Aquino, Francisco Júnior, Tyciane de Souza Nascimento · Pharmaceuticals · 2025

Showing 1 of 4 known citations — external sources report more than can currently be individually listed.

Related research

Article metrics

Real usage data collected on this platform.

40

Page views

0

PDF downloads

4

Outbound clicks

4

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.