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Research Article Open access CC BY 4.0

Nightmares Associated to Nevirapine during Chemoradiotherapy for Carcinoma Tongue

Bhooshan Zade, Vrushab Rao

International Journal of Medical and Pharmaceutical Case Reports · pp. 28–31 · Published 11 Apr 2024

10.9734/ijmpcr/2024/v17i2372

Abstract

Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) is a drug used in the management and treatment of HIV. It is considered safe for use in conjunction with platinum-based chemotherapy. Chemotherapy is a staple of cancer treatment and is used routinely in the management of malignancies of the head and neck. However, managing HIV-positive cancers presents challenges due to individual side effects and drug interactions. Drug interactions can potentiate or reduce drug metabolism, reduce excretion, or cause adverse drug reactions. Herein, we describe a case of new-onset nevirapine-induced nightmares that was noted in a patient undergoing chemoradiotherapy with cisplatin.

Case report nevirapine radiotherapy chemotherapy cisplatin toxicity adverse drug reactions

References (4)

  1. 1 The National Comprehensive Cancer Network [DOI]
  2. 2 Drug Interactions Between Antiretroviral Drugs and Comedicated Agents [DOI]
  3. 3 HIV Antiretroviral Therapy
  4. 4 Interaction of antitumor platinum complexes with human liver microsomal cytochromes P450 [DOI]

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