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Research Article Open access CC BY 4.0

Papillary Glioneuronal Tumor: A Case Report and a Brief Review

Amir Hossein Jafarian, Nema Mohammadian Roshan, Abbas Ali Omidi, Samaneh Boroumand-Noughabi

International Journal of Medical and Pharmaceutical Case Reports · pp. 70–75 · Published 22 Oct 2014

10.9734/IJMPCR/2015/13550

Abstract

Aims: Papillary glioneuronal Tumor (PGNT) is a rare, recently recognized glioneuronal tumor. To date only about 68 cases of PGNT have been reported. Although it has been regarded as a grade 1 neuronal – glial tumor by World Health Organization, aggressive cases have been reported and so, they can be challenging to diagnose and to treat as their relatively unclear clinical course. In this article, we summarize the clinical and pathological findings of this new entity. Presentation of Case: The patient was a 23-year-old man with headaches and right hemiparesis who had a tumor arising in close proximity of the anterior horn of the left lateral ventricle. No mitotic activity was identified, confirmed by Ki-67 labeling of about 1%. There was no evidence of recurrence during 64 month follow-up. A brief review of the other reported cases also has been included. Discussion and Conclusion: Although PGNT has been regarded as a grade 1 tumor, aggressive cases have been reported and their behavior has not been related to histological grading. So, all cases need to be reported to make further knowledge about its biological behavior.

Papillary glioneuronal tumor brain tumor central nervous system hemiparesis

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Cited by 2

Surgical Resection and Cellular Proliferation Index Predict Prognosis for Patients with Papillary Glioneuronal Tumor: Systematic Review and Pooled Analysis

Abdul-Kareem Ahmed, Hassan Y. Dawood, Jennifer Gerard · World Neurosurgery · 2017

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