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Research Article Open access CC BY 3.0

Phytomedicines of Sickle Cell Crisis in Mezam Division, Cameroon: Preventive and Curative Cares

Noumi Emmanuel, NFORBI Akonwi Ngwa Nebane

Journal of Pharmaceutical Research International · pp. 787–805 · Published 8 Feb 2014

10.9734/BJPR/2014/4959

Abstract

Background: The aim of this study was to survey the Mezam Division of Cameroon, with a view to documenting how the population of that area treat sickle cells disease using medicinal plants, and to determine the need for further information on sickle cell disease or sickle cell anaemia in that division. Method: Two questionnaires (one to patients and the other to traditional healers) were designed to gather information on every day life of patients and their parents, and medicinal plants were collected during the field trips. Results: Seventeen plants species belonging to 16 genera and 13 families were collected. They formed 12 recipes used to treat sickle cell by 5 traditional healers. With the help of these phytotherapists, we meet 92 former and new patients aged from 1 to 35 years old. The current symptoms of the disease were anaemia, hand and foot syndrome, splenomegaly and rheumatic pains. A rate of 52.2% of patients felt better after the treatment; 19.5% of patients with ongoing treatment, felt persistent symptoms; and 28.3% abandoned the treatment. Conclusion: Two haemoglobin diseases rage in Mezam Division and present some standard clinic demonstrations of anaemia hemolytic: HbS/S and HbS/C. The therapeutic preparations with Zanthoxylum zanthoxyloides exert an influence over haematopoietic organs like the spleen, by a dedifferentiation of its cells, and the production of Hb(α2, Ò¯2) which is the foetal haemoglobin. Thus the patient haemoglobins are S/S and F. This was observed in a patient aged 26 years old in 1999. Since that year, she is still symptom-free up to 2011. The main limitation of this research, however, may be used as a direction for future research, which is, assessing the results from the field at the chemical level in laboratories.

Hereditary disease sickle cell disease Phytomedicines Mezam Division Cameroon

References (13)

  1. 1 Herbal remedies of the Luo of Siaya District, Kenya: Establishing quantitative criteria for consensus [DOI]
  2. 2 Renal abnormalities in sickle cell disease [DOI]
  3. 3 THE NATURAL HISTORY OF ASYMPTOMATIC OSTEONECROSIS OF THE FEMORAL HEAD IN ADULTS WITH SICKLE CELL DISEASE [DOI]
  4. 4 Botanical methods in ethnopharmacology and the need for conservation of medicinal plants [DOI]
  5. 5 Phenylalanine is the Predominant Antisickling Agent inCajanus cajanSeed Extract [DOI]
  6. 6 The Sickle Cell Disease Patient
  7. 7 Chronic Liver Abnormalities in Sickle Cell Disease: A Clinicopathological Study in 70 Living Patients [DOI]
  8. 8 Membrane stability of sickle erythrocytes incubated in extracts of three medicinal plants: Anacardium occidentale, Psidium guajava, and Terminalia catappa [DOI]
  9. 9 Effects of aqueous extracts of Zanthoxylum macrophylla roots on membrane stability of human erythrocytes of different genotypes [DOI]
  10. 10 Assembly of Human Hemoglobin (Hb) β- and γ-Globin Chains Expressed in a Cell-free System with α-Globin Chains to Form Hb A and Hb F [DOI]
  11. 11 LONG BONE INVOLVEMENT IN SICKLE CELL ANEMIA [DOI]
  12. 12 Enumeration of the flowering plants of tropical Africa [DOI]
  13. 13 [Normal and abnormal cytological aspects of peripheral blood cells in neonates and young children].

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