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Research Article Open access CC BY 3.0

Placental Malaria and Its Associations with Pregnancy Outcome

V. E. Okolie, N. J. Obiechina, Z. C. Okechukwu, C. F. Oguejiofor, L. Okor, A. O. Onyegbule, L. S. A. Nwajiaku

International Journal of TROPICAL DISEASE & Health · pp. 766–772 · Published 7 May 2014

10.9734/IJTDH/2014/9911

Abstract

Background: Placental malaria constitutes a risk for both the pregnant women and their unborn child hence there is need to demonstrate the adverse associations between placental malaria and pregnancy outcome. Aim: To demonstrate the adverse maternal and fetal associations with placental malaria Study Design and Setting: This is a cross sectional study carried out at Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, South East, Nigeria between 1st August, 2012 and 31st January, 2013. Result: Two hundred placentae were analyzed, 141(70.5%) were positive for malaria, Placental malaria was associated with lower maternal pcv (30.67±1.60 vs 32.51±2.82, p-value < 0.001), preterm delivery (OR=4.99, C.I=1.15 – 45.08, p- value=0.020), and low birth weight (OR = 4.71, C.I=1.08 – 42.71, p-value=0.027) but not associated with maternal anaemia (OR=2.27, C.I= 0.90-6.47, p-value=0.063) and perinatal deaths (OR=Infinity, C.I =0.38 – infinity, p-value = 0.143). Conclusion: Placental malaria was associated with low birth weight, lower pcv and preterm delivery but associated neither with maternal anaemia nor perinatal deaths.

Placental malaria associations and pregnancy outcome

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Zainabur Rahmah, Teguh Wahju-Sardjono, Loeki Enggar Fitri · Iranian Journal of Parasitology · 2019

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