Prevalence of Endometrial Hyperplasia among Patients with Abnormal Uterine Bleeding: An Analysis from a Single Centre

Abstract

Background: Abnormal uterine bleeding (AUB) is a frequent cause for gynaecological consultations, often linked to underlying endometrial pathology. Endometrial hyperplasia (EH) is of clinical importance, particularly when atypia is present, due to its potential to progress to endometrial carcinoma (World Health Organization, 2014; Kurman et al., 2014). This study investigates the prevalence of EH in patients admitted with AUB at Sheri Kashmir Institute of Medical Sciences, Srinagar, J&K. Methods: A retrospective study was conducted, including 73 patients admitted with AUB who underwent endometrial biopsy. The prevalence of EH was assessed, with cases categorized as either hyperplasia without atypia or hyperplasia with atypia. Results: Out of the 73 patients, 28 cases (38.36%) were diagnosed with EH. Of these, 25 cases (34.25%) had hyperplasia without atypia, while 3 cases (4.1%) had hyperplasia with atypia, highlighting the importance of prompt evaluation in preventing progression to malignancy (American College of Obstetricians and Gynecologists, 2020; Miller et al., 2021). Conclusion: The findings underscore the necessity of histopathological assessment in AUB cases, especially for identifying atypical hyperplasia, which carries a higher risk of endometrial cancer (Reed et al., 2009; Huang et al., 2020). The study advocates for refining screening protocols and exploring tailored management strategies to optimize patient outcomes.