Protective Effect of Raphanus sativus Using by Phytochemical and Antiulcer Activity by Aspirin Induced  Gastric Ulcer

K. Hemamalini; Y Ramulu; B. Rambabu

doi:10.9734/jpri/2025/v37i17650

Research Article Open access CC BY 4.0

Protective Effect of Raphanus sativus Using by Phytochemical and Antiulcer Activity by Aspirin Induced Gastric Ulcer

K. Hemamalini, Y Ramulu, B. Rambabu

Journal of Pharmaceutical Research International · pp. 83–89 · Published 23 Jan 2025

10.9734/jpri/2025/v37i17650

Abstract

Raphanus sativus, a widely growing, has been used in traditional medicine for treating many ailments. The objective of the present study was to evaluate the effects of Aspirinic extract of R. Sativus leaves on gastric ulcer. The antiulcer effects of MERS at 100 and 200 mg/kg doses were evaluated on Aspirin gastric ulcer models. The histological changes in gastric tissue of ulcer mice were also determined in aspirin induced models. R. sativus treatment significantly (P < 0.01) reduced the ulcer index and significantly (P < 0.01) increased the gastric pH of both Aspirin and aspirin-induced ulcer mice. The observations confirm that MERS whole plant has antiulcer activities.

Raphanus sativus Ulcer gastric ulcer aspirin-induced ulcer

Cited by 1

1 citation reported by external sources — individual citing-article records aren't available to list yet.

Effect of Various Yoghurt Blends on Indomethacin-induced Ulcerogenic Wistar Rats — shares topic coverage
Histochemical Studies of the Efficacy of an Anti-Ulcer Herbal Mixture on the Gastrointestinal Tract of Albino Rats — shares topic coverage
Anti-ulcerogenic Activity of Aqueous Extract of Unripe Fruit of Musa sapientum Linn in Combination with Vitamin C on Ulcer Induced Models in Experimental Rats — shares topic coverage
Amilioretive Effect of Aqueous Leaves Extract of Ziziphus mucronata in Ethanol Induced Gastric Ulcer Model Rats — shares topic coverage
Analgesic, Non-ulcerogenic and Antioxidant Activities of the Aqueous Stem Bark Extract of Morinda lucida (Rubiaceae) in Mice — shares topic coverage

Access this article

View at publisher

Cite this article

K. Hemamalini, Y Ramulu, B. Rambabu (2025). Protective Effect of Raphanus sativus Using by Phytochemical and Antiulcer Activity by Aspirin Induced Gastric Ulcer. Journal of Pharmaceutical Research International , 83–89. https://doi.org/10.9734/jpri/2025/v37i17650

Affiliations

K. Hemamalini — Department of Pharmacology, Swami Vivekananda Institute of Pharmaceutical Sciences, Vangapally, Yadagirigutta, Yadadri- Bhuvangiri, India.
Y Ramulu — Department of Pharmaceutics, Sri Datta Institute of Pharmacy, Sheriguda, Hyderabad, India
B. Rambabu — Department of Toxicology, Virchow Biotech Private Limited, Hyderabad, Telangana State -500088, India.

Metrics

3
Views: 0
Downloads: 1
Citations: 0
Outbound

Full metrics

Article metrics

Real usage data collected on this platform.

3

Page views

0

PDF downloads

0

Outbound clicks

1

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.