Skip to content
Research Article Open access CC BY 4.0

Studies on Lectin Mediated Agglutination Reaction on Red Blood Cell Surface Antigens Using Hot and Cold Water Plant Extracts

Bhavya Sahithi Velagapudi, Hemanth Sai Nannapaneni, Akanksha Alampally, Suryanarayana Veeravilli, Duggipogu Praveen Kumar, Sai Prasad Kavuturi, Swarna Tejaswi Chodisetti, Nadeem Siddiqui

Journal of Pharmaceutical Research International · pp. 48–52 · Published 17 Dec 2021

10.9734/jpri/2021/v33i59B34351

Abstract

Lectin has various physiological roles in cell agglutination, based on their carbohydrate-binding properties, plant lectins are widely used for the detection, segregation, and characterization of glycoconjugates. Rhesus (Rh) factor is a protein that is inherited and found on the surface of red blood cells. If the surface protein is present, the RBC is Rh positive; otherwise, it is Rh-negative in nature. In this paper, we use agglutination reactions to investigate the effect of different cold and hot water extracted plants on RBC antigens as an alternative to commercial monoclonal antibodies. Extensive research on the sequence homology and 3-D structure of various plant lectins suggests that they have been conserved throughout evolution and may play important physiological roles that are still unknown.

Antigen agglutination reaction plant lectins RH factor RBC antigen

Cited by 0

No indexed citations yet.

Article metrics

Real usage data collected on this platform.

4

Page views

0

PDF downloads

0

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.