Skip to content
Research Article Open access CC BY 4.0

Study of Estimation of Urinary Delta Aminolevulinic Acid Levels as an Indicator of Lead Exposure in Pottery Workers

Neelam J. Patil, Sayali R. Kalokhe, Sachin A. Patharkar, Alka V. Nerurkar, Pradeep N. Surve, Umesh R. Shinde

Asian Journal of Medicine and Health · pp. 58–63 · Published 31 Jul 2020

10.9734/ajmah/2020/v18i830234

Abstract

Background: Lead toxicity is a significant environmental hazard and has widespread ill effects on human body. In this study we detected the lead exposure by measuring urinary delta aminolevulinic acid levels. The activity of delta aminolevulinic acid dehydratase enzyme is inhibited significantly by lead, which leads to an increase in urinary δ- ALA excretion. Hence we can use estimation of urinary δ-ALA levels as a surrogate marker of lead exposure in pottery workers. Aim: To estimate the urinary delta aminolevulinic acid levels in pottery workers as an index of lead exposure. Materials and Methods: The study was done on 85 pottery workers of age group between 18 to 50 years with their brief history related to lead exposure. Their urine samples were analysed for δ-ALA by Ehrlich method. Results: According to our observation, it was found that out of 85 urine samples; 58 samples showed increased urinary δ-ALA levels (68.23%). Conclusion: We conclude that the prevalence of lead exposure in pottery workers in Mumbai is very high. Good hygienic practices and necessary precautions should be followed to avoid its ill effects on human body.

Urinary delta aminolevulinic acid (δ–ALA) blood lead levels (BLL) lead poisoning in pottery workers.

References (6)

  1. 1 Identifying and managing adverse environmental health effects: 3. Lead exposure.
  2. 2 Simple Method for Determination of Urinary δ-Aminolevulinic Acid as an Index of Lead Exposure [DOI]
  3. 3 Status of Serum Calcium, Vitamin D and Parathyroid Hormone and Hematological Indices Among Lead Exposed Jewelry Workers in Dhaka, Bangladesh [DOI]
  4. 4 NORMAL LEVELS OF δ-AMINOLEVULINIC ACID IN THE SPOT URINES OF ADULT MEN, AS MEASURED BY A SIMPLIFIED METHOD [DOI]
  5. 5 High performance liquid chromatographic procedure for quantitative determination of urinary delta-aminolevulinic acid as indices of lead exposure [DOI]
  6. 6 Estimation of Urinary Delta Aminolevulinic Acid (δ-ALA) Levels in Students of Age Group 15 to 25 Years as an Index of Lead Exposure [DOI]

Cited by 3

Estimation of Urinary Lead and Urinary δ-Aminolevulinic Acid as an Index of Lead Exposure in Urban and Rural Residents of West Bengal, India

A. Yadav, A. Mukhopadhayay, Amit Chakrabarti · Indian Journal of Occupational and Environmental Medicine · 2024

Estimation of urinary delta aminolevulinic acid levels in gasoline and petrol pump workers as an index of lead exposure

S. Patharkar, Neelam J. Patil, S. Thorat · International Journal of Clinical Biochemistry and Research · 2022

Showing 2 of 3 known citations — external sources report more than can currently be individually listed.

Related research

Article metrics

Real usage data collected on this platform.

8

Page views

0

PDF downloads

5

Outbound clicks

3

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.