Synthesis of New 1,2,4-Triazoles Containing Oxadiazole Moiety: Potential Intermediates for Preparation of Ribavirin Analogues
Tatyana Sharonova, Sergey Baykov, Mikhail Dorogov
International Research Journal of Pure and Applied Chemistry · pp. 1–5 · Published 10 Nov 2015
10.9734/IRJPAC/2016/22429Abstract
In this paper, we report synthesis of the new biheterocycles containing 1,2,4-triazole and 1,2,4-oxadiazole or 1,3,4-oxadiazole moiety. Oxadiazole ring is bioisosteric replacement of carboxamide group. In future, these compounds will be used for enzymatic synthesis of ribavirin analogues. Structures of the final biheterocycles were confirmed by spectral and elemental analysis.
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