The New Pandemic Covid-19: Treatment Options and Developments
R. Gayatri, S. Lavanya, Meeran Hussain, John Veslin
Asian Journal of Biology · pp. 1–13 · Published 23 Jun 2020
10.9734/ajob/2020/v9i330086Abstract
SARS-CoV-2, the novel infectious causative factor of the new pandemic COVID-19 produced 5934936 total infected cases and 367166 death cases across multiple continents as of May 31, 2020. Majority of the world’s population are still vulnerable to COVID-19. As of now, there are no clear scientific proven treatment or drug to combat covid-19, but prevention and management can reduce the spread of virus. In this crisis, a vaccine, that can train the immune system to fight against this novel coronavirus becomes essential to control the further dissemination of the new pandemic COVID-19. This review provides insights into the on- going treatment options available for COVID-19 including antiviral drugs, Ayurvedic treatment, combination of drugs and plasma therapy. This review also aims to highlight on the development of vaccines and its clinical status.
References (48)
- 1 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [DOI]
- 2 A Novel Coronavirus from Patients with Pneumonia in China, 2019 [DOI]
- 3 A pneumonia outbreak associated with a new coronavirus of probable bat origin [DOI]
- 4 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study [DOI]
- 5 SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor [DOI]
- 6 COVID-19: consider cytokine storm syndromes and immunosuppression [DOI]
- 7 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster [DOI]
- 8 Pathological findings of COVID-19 associated with acute respiratory distress syndrome [DOI]
- 9 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro [DOI]
- 10 First Case of 2019 Novel Coronavirus in the United States [DOI]
- 11 The proximal origin of SARS-CoV-2 [DOI]
- 12 Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome [DOI]
- 13 Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus [DOI]
- 14 SARS and MERS: recent insights into emerging coronaviruses [DOI]
- 15 Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle [DOI]
- 16 Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology [DOI]
- 17 The Architecture of SARS-CoV-2 Transcriptome [DOI]
- 18 Coronaviruses post-SARS: update on replication and pathogenesis [DOI]
- 19 Therapeutic options for the 2019 novel coronavirus (2019-nCoV) [DOI]
- 20 Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings [DOI]
- 21 Updated understanding of the outbreak of 2019 novel coronavirus (2019‐nCoV) in Wuhan, China [DOI]
- 22 Baricitinib as potential treatment for 2019-nCoV acute respiratory disease [DOI]
- 23 Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study [DOI]
- 24 Tocilizumab treatment in COVID‐19: A single center experience [DOI]
- 25 SARS: Systematic Review of Treatment Effects [DOI]
- 26 Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase [DOI]
- 27 Phylogenetic network analysis of SARS-CoV-2 genomes [DOI]
- 28 Anti-HCV, nucleotide inhibitors, repurposing against COVID-19 [DOI]
- 29 SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway [DOI]
- 30 Emerging coronaviruses: Genome structure, replication, and pathogenesis [DOI]
- 31 Inhibition of SARS-CoV 3CL protease by flavonoids [DOI]
- 32 Emerging novel coronavirus (2019-nCoV)—current scenario, evolutionary perspective based on genome analysis and recent developments [DOI]
- 33 Trilogy of ACE2: A peptidase in the renin–angiotensin system, a SARS receptor, and a partner for amino acid transporters [DOI]
- 34 Profile of Specific Antibodies to the SARS-Associated Coronavirus [DOI]
- 35 Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2 [DOI]
- 36 Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion [DOI]
- 37 An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development [DOI]
- 38 Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro [DOI]
- 39 Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish Model [DOI]
- 40 CORONAVIRUS DISEASE 2019 (COVID-19) [DOI]
- 41 Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome [DOI]
- 42 A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [DOI]
- 43 Hydroxychloroquine-Inhibited Dengue Virus Is Associated with Host Defense Machinery [DOI]
- 44 Challenges of Convalescent Plasma Therapy on COVID-19 [DOI]
- 45 Efficacy of Natural Compounds from Tinospora cordifolia Against SARS-CoV-2 Protease, Surface Glycoprotein and RNA Polymerase [DOI]
- 46 G1-4A, a Polysaccharide from Tinospora cordifolia Inhibits the Survival of Mycobacterium tuberculosis by Modulating Host Immune Responses in TLR4 Dependent Manner [DOI]
- 47 Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV [DOI]
- 48 Probable Pangolin Origin of 2019-nCoV Associated with Outbreak of COVID-19 [DOI]
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