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Research Article Open access CC BY 4.0

The Potential for Acupuncture to Attenuate Hippocampal Apoptosis

Hana Marsheck, Yunsuk Koh

Asian Journal of Medicine and Health · pp. 35–47 · Published 10 Mar 2020

10.9734/ajmah/2020/v18i130178

Abstract

Aims: To evaluate the potential for acupuncture to help mediate hippocampal apoptosis. Study Design: Systematic Review. Methodology: A search was conducted through PubMed, Scopus and Web of Science using the keywords “hippocampus,” “apoptosis” and “acupuncture” and found 37 qualified articles from January 2009 to March 2019. Results: All of the qualifying studies reviewed strongly support that acupuncture decreases the incidence of hippocampal apoptosis. Conclusion: It was clear that acupuncture can positively affect hippocampal apoptosis. The most frequently suggested mechanism was decreased BAX expression and increased BCL-2 expression, often in the CA1 region of the hippocampus, although it was only seen in about 1/3 of the studies reviewed. Future studies are needed to further investigate the exact mechanism associated with acupuncture in hippocampal apoptosis.

Brain ischemia BCL-2-associated X protein expression B-cell lymphoma 2 expressions p38 mitogen-activated protein kinase pathway.

References (15)

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Cited by 1

Acupuncture Readiness Attitude Scale (ARAS): An Informal Screener for Patient Suitability for Acupuncture Treatment

Guo-Hui Xie, Meng Kiat Tan, Jennifer Erin Camulli · Journal of Complementary and Alternative Medical Research · 2024

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