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Research Article Open access CC BY 4.0

Through Indian Eyes: A Case Series on Steroid-induced Secondary Cataract

B S Girish, C S Meghana, Joel M. Johns, R. Srinivasan

International Journal of Medical and Pharmaceutical Case Reports · pp. 8–12 · Published 26 Mar 2024

10.9734/ijmpcr/2024/v17i2367

Abstract

Lichen planus, a chronic autoimmune dermatological disorder, often necessitates the use of topical corticosteroids for symptom management. However, this case series highlights the emergence of topical steroid-induced secondary cataracts in two patients, emphasizing a previously underrecognized complication. Both patients, females aged 36 and 43, presented with gradual vision loss in their left eyes, attributed to prolonged corticosteroid use for lichen planus and skin allergies, respectively. Ophthalmological examinations confirmed the diagnosis, leading to cataract surgeries. The pathogenesis involves complex cellular and molecular mechanisms, emphasizing the need for vigilant monitoring during corticosteroid therapy. Moreover, the lack of stringent reporting systems for adverse drug reactions in India underscores the necessity for comprehensive monitoring to mitigate economic and quality of life burdens. The study emphasizes the importance of judicious corticosteroid use, tapering regimens, and patient education to minimize complications while effectively managing dermatological conditions. This underscores the critical need for heightened awareness, surveillance, and patient-centred approaches to mitigate the risk of corticosteroid-induced secondary cataracts, ensuring optimal therapeutic outcomes and long-term ocular health.

Steroid-Induced cataract corticosteroids corticosteroid therapy cataract formation

References (13)

  1. 1 Lichen Planus [DOI]
  2. 2 The prevalence and risk factors for cataract in rural and urban India [DOI]
  3. 3 Lichen planus – a clinical guide [DOI]
  4. 4 Review of Nail Lichen Planus [DOI]
  5. 5 Sémiologie et formes cliniques de la cataracte chez l’adulte [DOI]
  6. 6 Drugs associated with cataract formation represent an unmet need in cataract research [DOI]
  7. 7 Inhaled Corticosteroid Exposure and Risk of Cataract in Patients with Asthma and COPD: A Systematic Review and Meta‐Analysis [DOI]
  8. 8 Role of Chondroitin Sulfate Proteoglycan 5 in Steroid-Induced Cataract [DOI]
  9. 9 Cataract Risk and Topical Corticosteroids among Children with Juvenile Idiopathic Arthritis-Related Uveitis [DOI]
  10. 10 Frequency of posterior cataract in steroid-dependent or frequent relapse nephrotic syndrome in children. [DOI]
  11. 11 Assessment of the Level of Knowledge and Awareness of the Risk of Chronic Use of Steroids in Causing Cataracts Among the General Population in the Western Region of the Kingdom of Saudi Arabia (KSA): A Cross-Sectional Study [DOI]
  12. 12 Atopic dermatitis, cutaneous steroids and cataracts in children: two case reports [DOI]
  13. 13 Global, Regional, national Burden and Gender Disparity of Cataract: Findings From the Global Burden of Disease Study 2019 [DOI]

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