Aim: To analyze the active sites of the proofreading (PR) functions in the multisubunit DNA-dependent RNA polymerases (MSU RNAPs) from prokaryotes, chloroplasts and eukaryotes, and propose a plausible unified catalytic mechanism for these enzymes. Study Design: Data collected on...
Open access
Research Article10.9734/ijbcrr/2021/v30i730278
Aim: The Mitochondrial transcription factor A (TFAM) and mitochondrial (mt) DNA copy number variations are known to contribute in disease development. Genetic factors play an important role in the development of endometriosis. Therefore, this case–control study aimed to analyze t...
Open access
Research Article10.9734/ijbcrr/2021/v30i730279
Background and Objectives: Guava (Psidium guajava) belongs to the family Myrtaceae. It has been cultivated in Nigeria one of the most common fruits in Nigeria. It has become popular because of its availability almost throughout the year. The objective of this study is to evaluate...
Open access
Research Article10.9734/ijbcrr/2021/v30i730277
Methaemoglobin (Met-Hb) is a type of the oxygen-carrying metalloproteinhemoglobin. The heme group iron exists as ferric (Fe3+) iron, rather than the ferrous (Fe2+) iron of typical hemoglobin. Met-Hb is unable to perform the function of binding to oxygen like oxyhaemoglobin does....
Open access
Research Article10.9734/ijbcrr/2021/v30i730276
Vicky Ama Moor, Liliane Mfeukeu Kuate, Manuela Eko, Daryl N. Tcheutchoua, Mbono Samba, Jan Réné Nkeck, Christian Ouankou Ngongang, Virginie Poka, Batakeh Ba Agoons, Honoré Kemnang, Eric Yone Pefura & Alain Menanga·International Journal of Biochemistry Research & Review·2021
Background: Heart failure (HF) and Chronic Obstructive Pulmonary Disease (COPD) are two conditions frequently responsible of dyspnea. The clinical distinction between these two etiologies is challenging in clinical practice, particularly in developing countries where access to im...
Open access
Research Article10.9734/ijbcrr/2021/v30i630275
Raquel Martins De Freitas, Christina Pacheco, Stela Mirla Da Silva Felipe, Jannison Karlly Ribeiro Cavalcante, Paulo Elesson Oliveira, Denner Silvino Da Silva & Vânia Marilande Ceccatto·International Journal of Biochemistry Research & Review·2021
Aims: The present study aimed to identify miRNAs differentially expressed in rats submitted to strenuous exercise and in silico investigation of the biological implication of the findings. Place and Duration of Study: The in vivo experiments and analyses were performed in the Lab...
Open access
Research Article10.9734/ijbcrr/2021/v30i630274
Aims: Ethyl acetate fraction of total phenols from Zanthoxylum zanthoxyloides leaves was evaluated for its effects in alloxan-induced diabetic male albino rats. Methodology: Diabetes was induced in rats by administrating alloxan monohydrate at a dose of 130 mg/kg body weight. The...
Open access
Research Article10.9734/ijbcrr/2021/v30i630273
Aims: The aim of this study is to evaluate the content of phenolic compounds, antioxidant and 15-lipoxygenase inhibition effects of methanolic extract and its fractions of Daniellia. oliveri stem bark. Place and Duration of Study: The work was carried out in the Department of Tra...
Open access
Research Article10.9734/ijbcrr/2021/v30i630271
Objective: The present study aims to constitute a database necessary for the efficient valorisation of the local cultivated edible mushrooms in the Ivorian diet. This work consisted in evaluating the biochemical characteristics and microbiology analysis of cultivated Pleurotus os...
Open access
Research Article10.9734/ijbcrr/2021/v30i630270
Background: A staple for about 800 million people in tropical countries, cassava contains a high content of hydrocyanic acid making it toxic. Objective: This study was proposed to test the conservation effectiveness on tuber toxicity. Materials and Methods: Tests were carried out...
Open access
Research Article10.9734/ijbcrr/2021/v30i530269
The present study investigated the phytochemistry and antioxidant activity of Pterocarpus angolensis (Mubvamaropa) from Mupandawana. Pt. angolensis has numerous medicinal uses. The bark, sap, leaves and roots are all used to treat different ailments. The sap is used to stop nose...
Open access
Research Article10.9734/ijbcrr/2021/v30i530267
Mabintou Diomande, Kouassi Hubert Konan, Yapo Thierry Monnet, Kouassi Armand Kanga, Jean Bedel Fagbohoun, Jaures Oscar Gbotognon, Eugène Jean Parfait Kouadio & Lucien Patrice Kouamé·International Journal of Biochemistry Research & Review·2021
Aims: During the industrial processing of mango, considerable quantities of peel and seeds are rejected, which results in a significant economic loss for the manufacturer, as well as an impact on the environment. However, mango almond and peel flours present enormous nutritional...
Open access
Research Article10.9734/ijbcrr/2021/v30i530266
Introduction: Anemia is one of the most common complications of kidney failure. The kidney is responsible for the production of erythropoietin, a key hormone in erythropoiesis. Insufficient production of erythropoietin due to impaired kidney functions and also inflammation could...
Open access
Research Article10.9734/ijbcrr/2021/v30i530265
Irina Lydia Sudeu Nitcheu, Thomas Djifack Tadongfack, Falmata Amazia, Melissa Guechoun Choundong, Marthe Pelagie Alogo, Paul Talla, Batakeh B. Agoons & Vicky Jocelyne Ama Moor·International Journal of Biochemistry Research & Review·2021
Background: Inflammatory bowel diseases (IBDs) are relatively common in African countries. The use of faecal markers, Calprotectin in particular, is presently of considerable interest to IBD patients. The high faecal calprotectin level has a good diagnostic accuracy in discrimina...
Open access
Research Article10.9734/ijbcrr/2021/v30i530264
Background: Chrysophyllum albidum has been widely consumed for its flesh part as a fruit snack and source of vitamins but also grossly under-utilized because of dearth of knowledge on nutritional and therapeutic potencies of other fruit parts. This study thus aimed to comparative...
Open access
Research Article10.9734/ijbcrr/2021/v30i430263