Cancer a leading cause of human mortality worldwide is characterised by the unseemly growth of cellular mass and signalled through the enlargement of stress. Management of cancer treatment is still buried and has been recently alerting the need to discover a drug molecule with l...
Open access
Research Article10.9734/ijbcrr/2019/v26i330099
Aim: To analyze the most complex multi-subunit (MSU) DNA dependent RNA polymerases (RNAPs) of eukaryotic organisms and find out conserved motifs, metal binding sites and catalytic regions and propose a plausible mechanism of action for these complex eukaryotic MSU RNAPs, using ye...
Open access
Research Article10.9734/ijbcrr/2019/v26i330097
Aim: Cough due to Klebsiella pneumoniae and Streptococcus pneumoniae is currently managed by conventional antibiotics and herbal extracts in Uganda. However, much as these herbal extracts are extensively used, their antibacterial activity is not known. This study aimed at determi...
Open access
Research Article10.9734/ijbcrr/2019/v26i230095
Fibrates are a class of medication that mainly lowers the blood triglyceride levels. They reduce the LDL and increase the levels of HDL C, in the blood. Clofibrate, the first member to be discovered in 1962 , and introduced in USA in 1967, is withdrawn in 2002, due to unexplaine...
Open access
Research Article10.9734/ijbcrr/2019/v26i230094
Aim: For centuries, plant and plant products have played a pivotal role in medication. This study evaluated the effect of aqueous extract of black seed (Nigella sativa) and uziza leaf (Piper guineense) on electrolytes, urea and creatinine of Wistar rats. Materials and Methods: Tw...
Open access
Research Article10.9734/ijbcrr/2019/v26i230092
Background: Diabetes mellitus is the one of the most common endocrine diseases that is characterized by hyperglycemia, altered metabolism with an increased risk of much complications. Besides drugs classically used for the treatment of diabetes several species of plants have been...
Open access
Research Article10.9734/ijbcrr/2019/v26i230093
Nowadays, many medicinal plants have proved effective in combating the phenomenon of bacterial multi-resistance against conventional antibiotics. However, the use of these plants, traditionally is done without precise doses. And this inaccuracy of dose is a real problem of tradit...
Open access
Research Article10.9734/ijbcrr/2019/v26i230090
Discussions about what is life continue to struggle; there are pros and cons for whether a virus is alive. However, an opposite thing – cell death – appears to be tantamount important and equally not-easygoing to define. Nevertheless, our current knowledge about eukaryotic cell d...
Open access
Research Article10.9734/ijbcrr/2019/v26i130089
Maize is a major crop in China and maize production in Heilongjiang Province ranks No.1 in the country in annual maize production in the whole country. Maize is prone to invasion by fungi and mycotoxins produced by these fungi are proven to be serious threats to animals as well a...
Open access
Research Article10.9734/ijbcrr/2019/v26i130088
Lead is a heavy metal found in earth’s crust. It is a widespread and insidious environmental toxin known as a severe and aggressive contaminant to human and animal organisms’ health status. This work is aimed at evaluating the effect of aqueous extract of Ocimum gratissimum (OG)...
Open access
Research Article10.9734/ijbcrr/2019/v26i130087
Rice is a major food crop in China and Japonica rice production in Heilongjiang Province ranks No.1 in total annual rice production in the country. Rice is prone to invasion by fungi and mycotoxins produced by the fungi are proven to be serious threats to human health. The object...
Open access
Research Article10.9734/ijbcrr/2019/v26i130086
Aims: To detect the adulterant in edible oil rapidly. Study Design: Authenticity and adulteration detection in edible oils are the increasing challenges for researchers, consumers, industries and regulatory agencies. Traditional approaches may not be the most effective option to...
Open access
Research Article10.9734/ijbcrr/2019/v26i130085
This study was carried out to determine the antimicrobial activity of silver nanoparticles synthesized using goat milk against pathogens of selected vegetables. Synthesis of Silver nanoparticles was done using Goat milk, and characterized using Ultra Violet-Visible absorption spe...
Open access
Research Article10.9734/ijbcrr/2019/v25i430084
The presence of fat, beyond physiological limits, in organs, other than the adipose tissue, like the liver, the skeletal muscle, the heart and the pancreas etc is called ectopic fat. It causes specific organ dysfunction in the tissues concerned. The importance of the ectopic fat...
Open access
Research Article10.9734/ijbcrr/2019/v25i430083
Aims: Lipids serve several important physiologic functions like energy homeostasis or biosynthesis of hormone within the human body. The deterioration of lipid metabolism which is favoured by menopause is the source of cardiovascular diseases. This study aimed to determine the pl...
Open access
Research Article10.9734/ijbcrr/2019/v25i430081